Indapamide EP Impurity A

Chemical stability and interactions in a new antihypertensive mixture containing indapamide and dihydralazine using FT-IR, HPLC and LC-MS methods
Anna GumieniczekORCID a, Justyna Galezaa, Anna Bereckaa, Tomasz Mroczekb, Krzysztof Wojtanowskib, Katarzyna Lipskaa and Joanna Skarbek
RSC Adv., 2018, 8, 36076–36089
 
A Stability Indicating UHPLC Method for the Simultaneous Estimation of Perindopril, Indapamide in Presence of Potential Impurities: An Application of QbD for Robustness Study
T.S.S. Jagan Mohan , Hitesh A Jogia & Khagga Mukkanti
TACL 10 (4) 2020 pp 477 – 497
 
Molecular Dynamics and Physical Stability of Coamorphous Ezetimib and Indapamide Mixtures
J. Knapik, Z. Wojnarowska, K. Grzybowska, K. Jurkiewicz, L. Tajber, and M. Paluch
Mol. Pharmaceutics 2015, 12, 10, 3610–3619

Indapamide EP Impurity A is chemically (2RS)-2-Methyl-1-nitroso-2,3-dihydro-1H-indole. It is also known as Indapamide USP Related Compound D. Indapamide EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Indapamide EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Indapamide.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.