Melphalan D8

SZ CAT No:	SZ-M003D02
CAS No	1212797-43-7
Mol.F.	C13H10D8Cl2N2O2
Mol.Wt.	313.3
Inv. Status	Custom Synthesis
Rel. CAS No	1217854-43-7 (HCl salt)

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Chemical Name: (S)-2-amino-3-(4-(bis(2-chloroethyl-1,1,2,2-d4)amino)phenyl)propanoic acid

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: ClC([2H])([2H])C([2H])([2H])N(C1=CC=C(C[C@H](N)C(O)=O)C=C1)C([2H])([2H])C([2H])([2H])Cl

Determination of melphalan by micelle enhanced spectrofluorimetric method: application to content uniformity testing and human plasma
By Sambhani, Naga Gayatri; Biju, Valsala Madhavan Nair
From Tenside, Surfactants, Detergents (2020), 57(1), 40-44

Rapid and simple flow injection analysis tandem mass spectrometric method for the quantification of melphalan in a lipid-based drug delivery system
By Mohammed-Saeid, Waleed; Michel, Deborah; Badea, Ildiko; El-Aneed, Anas
From Rapid Communications in Mass Spectrometry (2017), 31(18), 1481-1490

Melphalan D8 is chemically (S)-2-amino-3-(4-(bis(2-chloroethyl-1,1,2,2-d4)amino)phenyl)propanoic acid. Melphalan D8 is supplied with detailed characterization data compliant with regulatory guideline. Melphalan D8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Melphalan.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Related products

Melphalan EP Impurity A Hydrochloride

SZ CAT No:	: SZ-M003002
CAS No	: 1818258-87-5
Mol.F.	: C13H20N2O4 : HCl
Mol.Wt.	: 268.3 : 36.5
Inv. Status	: Out of Stock
Rel. CAS No	: 72143-20-5 (free base)

Melphalan EP Impurity B Hydrochloride

SZ CAT No:	: SZ-M003003
CAS No	: NA
Mol.F.	: C13H18N2O3 : HCl
Mol.Wt.	: 250.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1270153-04-2 (free base)

Melphalan EP Impurity C Hydrochloride

SZ CAT No:	: SZ-M003004
CAS No	: 2286317-87-9
Mol.F.	: C11H15ClN2O2 : HCl
Mol.Wt.	: 242.7 : 36.5
Inv. Status	: Limited Stock
Rel. CAS No	: 573704-41-3 (free base)

Melphalan EP Impurity D Hydrochloride

SZ CAT No:	: SZ-M003005
CAS No	: 1818258-86-4
Mol.F.	: C13H19ClN2O3 : HCl
Mol.Wt.	: 286.8 : 36.5
Inv. Status	: Limited Stock
Rel. CAS No	: 61733-01-5 (free base)

Melphalan EP Impurity E

SZ CAT No:	: SZ-M003006
CAS No	: NA
Mol.F.	: C15H23ClN2O3
Mol.Wt.	: 314.8
Inv. Status	: In Stock

Melphalan EP Impurity F Hydrochloride

SZ CAT No:	: SZ-M003007
CAS No	: NA
Mol.F.	: C13H17Cl3N2O2 : HCl
Mol.Wt.	: 339.6 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 2724878-97-9 (free base)

Melphalan EP Impurity G TFA salt

SZ CAT No:	: SZ-M003008
CAS No	: NA
Mol.F.	: C26H35Cl3N4O4 : 2(C2HF3O2)
Mol.Wt.	: 573.9 : 2(114.0)
Inv. Status	: In Stock
Rel. CAS No	: 2238824-43-4 (free base) ; 2238824-44-5 (HCl salt)

Melphalan EP Impurity H Hydrochloride

SZ CAT No:	: SZ-M003009
CAS No	: 62978-52-3
Mol.F.	: C14H20Cl2N2O2 : HCl
Mol.Wt.	: 319.2 : 36.5
Inv. Status	: Out of Stock, Custom Synthesis
Rel. CAS No	: 88457-23-2 (free base)

Melphalan

SZ CAT No:	: SZ-M003001
CAS No	: 148-82-3
Mol.F.	: C13H18Cl2N2O2
Mol.Wt.	: 305.2
Inv. Status	: In Stock
Rel. CAS No	: 3223-07-2 (HCl salt) ; 27960-54-9 (Na salt) ; 1559066-79-3 (Sulfate salt)

Melphalan EP Impurity I Hydrochloride

SZ CAT No:	: SZ-M003010
CAS No	: NA
Mol.F.	: C14H21ClN2O3 : HCl
Mol.Wt.	: 300.8 : 36.5
Inv. Status	: Out of Stock, Custom Synthesis
Rel. CAS No	: 573704-40-2 (free base)

Melphalan EP Impurity J Hydrochloride

SZ CAT No:	: SZ-M003011
CAS No	: NA
Mol.F.	: C15H22Cl2N2O3 : HCl
Mol.Wt.	: 349.3 : 36.5
Inv. Status	: Out of Stock
Rel. CAS No	: 2724549-95-3 (free base)

Melphalan EP Impurity K

SZ CAT No:	: SZ-M003012
CAS No	: 109-89-7
Mol.F.	: C4H11N
Mol.Wt.	: 73.1
Inv. Status	: In Stock
Rel. CAS No	: 660-68-4 (HCl salt)

Melphalan D-Isomer

SZ CAT No:	: SZ-M003013
CAS No	: 4213-32-5
Mol.F.	: C13H18Cl2N2O2 : HCl
Mol.Wt.	: 305.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 13045-94-8 (Free base)

Melphalan Racemic Mixture

SZ CAT No:	: SZ-M003014
CAS No	: 1465-26-5
Mol.F.	: C13H18Cl2N2O2 : HCl
Mol.Wt.	: 305.2 : 36.5
Inv. Status	: Out of Stock
Rel. CAS No	: 531-76-0 (Free base)

rac-Melphalan N-Oxide Impurity HCl

SZ CAT No:	: SZ-M003015
CAS No	: 685898-44-6
Mol.F.	: C13H18Cl2N2O3 : 2(HCl)
Mol.Wt.	: 321.2 : 2(36.5)
Inv. Status	: Out of Stock
Rel. CAS No	: 685847-78-3 (free base)

4-Nitro-L-Phenylalanine

SZ CAT No:	: SZ-M003016
CAS No	: 949-99-5
Mol.F.	: C9H10N2O4
Mol.Wt.	: 210.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 906813-62-5 (HCl salt) ; 897364-93-1 (HBr salt) ; 77918-94-6 (Na salt) ; 1170997-57-5 (Sulfate salt)

L-3-Nitrophenylalanine

SZ CAT No:	: SZ-M003017
CAS No	: 19883-74-0
Mol.F.	: C9H10N2O4
Mol.Wt.	: 210.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 170157-54-7 (HCl salt)

L-2-Nitrophenylalanine

SZ CAT No:	: SZ-M003018
CAS No	: 19883-75-1
Mol.F.	: C9H10N2O4
Mol.Wt.	: 210.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 35987-87-2 (HCl salt)

Melphalan Impurity 4

SZ CAT No:	: SZ-M003019
CAS No	: 2816794-87-1
Mol.F.	: C13H18N2O6
Mol.Wt.	: 298.3
Inv. Status	: Custom Synthesis

Melphalan Impurity 5

SZ CAT No:	: SZ-M003020
CAS No	: 17451-66-0
Mol.F.	: C17H12N2O6
Mol.Wt.	: 340.3
Inv. Status	: Custom Synthesis

Melphalan Impurity 6

SZ CAT No:	: SZ-M003021
CAS No	: 1951445-22-9
Mol.F.	: C13H16Cl2N2O4
Mol.Wt.	: 335.2
Inv. Status	: Custom Synthesis

Melphalan Impurity 7

SZ CAT No:	: SZ-M003022
CAS No	: NA
Mol.F.	: C17H14N2O4
Mol.Wt.	: 310.3
Inv. Status	: Custom Synthesis

Melphalan Impurity 8

SZ CAT No:	: SZ-M003023
CAS No	: 74743-22-9
Mol.F.	: C18H14N2O6
Mol.Wt.	: 354.3
Inv. Status	: Custom Synthesis

Melphalan Impurity 9

SZ CAT No:	: SZ-M003024
CAS No	: NA
Mol.F.	: C17H12N2O3
Mol.Wt.	: 292.3
Inv. Status	: Custom Synthesis

Melphalan Impurity 10

SZ CAT No:	: SZ-M003025
CAS No	: NA
Mol.F.	: C17H13N3O3
Mol.Wt.	: 307.3
Inv. Status	: Custom Synthesis

Melphalan Impurity 11

SZ CAT No:	: SZ-M003026
CAS No	: 40615-17-6
Mol.F.	: C9H10N2O
Mol.Wt.	: 162.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 35849-31-1 (HCl salt)

Melphalan Impurity 12

SZ CAT No:	: SZ-M003027
CAS No	: NA
Mol.F.	: C13H17Cl2N3O
Mol.Wt.	: 302.2
Inv. Status	: Custom Synthesis

Melphalan Impurity 13

SZ CAT No:	: SZ-M003028
CAS No	: NA
Mol.F.	: C13H15ClN2O4
Mol.Wt.	: 298.7
Inv. Status	: Custom Synthesis

Melphalan Impurity 14

SZ CAT No:	: SZ-M003029
CAS No	: 1088-80-8
Mol.F.	: C13H18Cl2N2O2
Mol.Wt.	: 305.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 4213-35-8 (HCl salt)

Melphalan Isopropyl Ester Hydrochloride

SZ CAT No:	: SZ-M003031
CAS No	: 757234-98-3
Mol.F.	: C16H24Cl2N2O2 : HCl
Mol.Wt.	: 347.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 104874-57-9 (free base)

2-(2-Chloro ethoxy) Ethyl acetate

SZ CAT No:	: SZ-M003032
CAS No	: 14258-40-3
Mol.F.	: C6H11ClO3
Mol.Wt.	: 166.6
Inv. Status	: In Stock

Melphalan Ethyl Ester

SZ CAT No:	: SZ-M003033
CAS No	: 112117-81-4
Mol.F.	: C15H22Cl2N2O2 : HCl
Mol.Wt.	: 333.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 18067-07-7 (free base) ; 189744-29-4 (TFA salt)

Methoxy Hydroxy Melphalan

SZ CAT No:	: SZ-M003034
CAS No	: NA
Mol.F.	: C14H22N2O4
Mol.Wt.	: 282.3
Inv. Status	: Out of Stock

Melphalan D8 Hydrochloride

SZ CAT No:	: SZ-M003D01
CAS No	: 1217854-43-7
Mol.F.	: C13H10D8Cl2N2O2 : HCl
Mol.Wt.	: 313.3 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1212797-43-7 (free base)

Melphalan D8

SZ CAT No:	: SZ-M003D02
CAS No	: 1212797-43-7
Mol.F.	: C13H10D8Cl2N2O2
Mol.Wt.	: 313.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1217854-43-7 (HCl salt)

Melphalan Hydrochloride

SZ CAT No:	: SZ-M003030
CAS No	: 3223-07-2
Mol.F.	: C13H18Cl2N2O2 : HCl
Mol.Wt.	: 305.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 148-82-3 (free base) ; 27960-54-9 (Na salt) ; 1559066-79-3 (Sulfate salt)

Melphalan Sodium salt

SZ CAT No:	: SZ-M003035
CAS No	: 27960-54-9
Mol.F.	: C13H18Cl2N2O2 : Na
Mol.Wt.	: 305.3 : 23.0
Inv. Status	: Custom Synthesis
Rel. CAS No	: 3223-07-2 (HCl salt) ; 148-82-3 (free base) ; 1559066-79-3 (Sulfate salt)

Melphalan Sulfate salt

SZ CAT No:	: SZ-M003036
CAS No	: 1559066-79-3
Mol.F.	: C13H18Cl2N2O2 : H2SO4
Mol.Wt.	: 305.3 : 98.1
Inv. Status	: Custom Synthesis
Rel. CAS No	: 3223-07-2 (HCl salt) ; 27960-54-9 (Na salt) ; 148-82-3 (free base)

Melphalan Impurity 15

SZ CAT No:	: SZ-M003047
CAS No	: 67877-95-6
Mol.F.	: C10H12N2O4
Mol.Wt.	: 224.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 122079-30-5 (free base)

Isopropoxy Melphalan

SZ CAT No:	: SZ-M003049
CAS No	: NA
Mol.F.	: C16H25ClN2O3 : HCl
Mol.Wt.	: 328.8 : 36.5
Inv. Status	: Custom Synthesis

Melphalan Impurity 16

SZ CAT No:	: SZ-M003050
CAS No	: 176794-96-0
Mol.F.	: C15H20N2O6
Mol.Wt.	: 324.3
Inv. Status	: Custom Synthesis

Melphalan Impurity 17

SZ CAT No:	: SZ-M003051
CAS No	: 114346-32-6
Mol.F.	: C15H20N2O6
Mol.Wt.	: 324.3
Inv. Status	: Custom Synthesis

Melphalan Impurity 18

SZ CAT No:	: SZ-M003052
CAS No	: 114346-36-0
Mol.F.	: C15H20N2O6
Mol.Wt.	: 324.3
Inv. Status	: Custom Synthesis

Melphalan Dimer Impurity

SZ CAT No:	: SZ-M003053
CAS No	: NA
Mol.F.	: C37H56N4O11
Mol.Wt.	: 732.9
Inv. Status	: Custom Synthesis

Melphalan Ethoxy-Alcohol Impurity

SZ CAT No:	: SZ-M003054
CAS No	: NA
Mol.F.	: C21H34N2O7
Mol.Wt.	: 426.5
Inv. Status	: Custom Synthesis

Melphalan D8

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