Lumefantrine USP Related Compound A

SZ CAT No:	SZ-L058018
CAS No	NA
Mol.F.	C30H32Cl3NO : HCl
Mol.Wt.	528.9 : 36.5
Inv. Status	Custom Synthesis
Rel. CAS No	2170653-95-7 (free base)

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Chemical Name: ((RS, Z)-2-(Dibutylamino)-2-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol hydrochloride) (as per USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: ClC1=CC=C(C=C1)/C=C2C3=C(C4=C\2C=C(Cl)C=C4)C(C(N(CCCC)CCCC)CO)=CC(Cl)=C3.Cl

Stability-indicating HPLC-DAD/UV-ESI/MS impurity profiling of the anti-malarial drug lumefantrine
Mathieu Verbeken1† , Sultan Suleman1,3† , Bram Baert1 , Elien Vangheluwe1 , Sylvia Van Dorpe1 , Christian Burvenich2 , Luc Duchateau2 , Frans H Jansen4 , Bart De Spiegeleer
Verbeken et al. Malaria Journal 2011, 10:51 Page 2 of 9

Analytical Method Development and Validation for Estimation of Lumifantrine in Pharmaceutical Dosage Forms by HPLC
Naveen S Kotur *1 ,Singaravel Sivasamy2 , S.Srinivasan
J. Pharm. Sci. & Res. Vol.4(1), 2012,1672-1675

A Modified Method for Determination of Lumefantrine in Human Plasma by HPLC-UV and Combination of Protein Precipitation and Solid-Phase Extraction: Application to a Pharmacokinetic Study
Liusheng Huang, Patricia S. Lizak, Anura L. Jayewardene, Florence Marzan, Ming-Na Tina Lee and Francesca T. Aweeka
Analytical Chemistry Insights 2010:5 15–23

Lumefantrine USP Related Compound A is chemically ((RS, Z)-2-(Dibutylamino)-2-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol hydrochloride) (as per USP). Lumefantrine USP Related Compound A is supplied with detailed characterization data compliant with regulatory guideline. Lumefantrine USP Related Compound A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lumefantrine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Lumefantrine USP Related Compound A

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SZ CAT No:	: SZ-L058001
CAS No	: 82186-77-4
Mol.F.	: C30H32Cl3NO
Mol.Wt.	: 528.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-L058002
CAS No	: 1331642-68-2
Mol.F.	: C30H32Cl3NO
Mol.Wt.	: 528.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-L058003
CAS No	: 1795129-61-1
Mol.F.	: C44H24Cl6O2
Mol.Wt.	: 797.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-L058004
CAS No	: 1795128-25-4
Mol.F.	: C44H24Cl6O2
Mol.Wt.	: 797.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-L058005
CAS No	: 7012-16-0
Mol.F.	: C13H8Cl2
Mol.Wt.	: 235.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-L058006
CAS No	: 252990-29-7
Mol.F.	: C22H13Cl3O
Mol.Wt.	: 399.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-L058007
CAS No	: 4364-35-6
Mol.F.	: C20H11Cl3
Mol.Wt.	: 357.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-L058008
CAS No	: NA
Mol.F.	: C30H30Cl3N
Mol.Wt.	: 510.9
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-L058009
CAS No	: NA
Mol.F.	: C30H33Cl3NO2
Mol.Wt.	: 545.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-L058010
CAS No	: NA
Mol.F.	: C30H32Cl3NO2
Mol.Wt.	: 544.9
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-L058011
CAS No	: 69759-61-1
Mol.F.	: C23H29Cl2NO
Mol.Wt.	: 406.4
Inv. Status	: In Stock
Rel. CAS No	: 53221-07-1 (HCl salt)

SZ CAT No:	: SZ-L058012
CAS No	: 355841-11-1
Mol.F.	: C26H24Cl3NO
Mol.Wt.	: 472.8
Inv. Status	: In Stock

SZ CAT No:	: SZ-L058013
CAS No	: 53221-25-3
Mol.F.	: C23H27Cl2NO2
Mol.Wt.	: 420.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-L058014
CAS No	: 53221-07-1
Mol.F.	: C23H29Cl2NO : HCl
Mol.Wt.	: 406.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 69759-61-1 (free base)

SZ CAT No:	: SZ-L058015
CAS No	: 53221-14-0
Mol.F.	: C15H10Cl2O
Mol.Wt.	: 277.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-L058016
CAS No	: 1456736-33-6
Mol.F.	: C30H32Cl3NO
Mol.Wt.	: 528.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-L058017
CAS No	: NA
Mol.F.	: C44H24Cl6O2 : C44H24Cl6O2
Mol.Wt.	: 797.4 : 797.4
Inv. Status	: Limited Stock

SZ CAT No:	: SZ-L058018
CAS No	: NA
Mol.F.	: C30H32Cl3NO : HCl
Mol.Wt.	: 528.9 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2170653-95-7 (free base)

SZ CAT No:	: SZ-L058019
CAS No	: 1276121-35-7
Mol.F.	: C30H33Cl2NO
Mol.Wt.	: 494.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-L058020
CAS No	: 252990-19-5
Mol.F.	: C26H24Cl3NO
Mol.Wt.	: 472.8
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-L058021
CAS No	: NA
Mol.F.	: C26H23Cl3N2O2
Mol.Wt.	: 501.8
Inv. Status	: Custom Synthesis