Leflunomide EP Impurity B

SZ CAT No:	SZ-L032003
CAS No	163451-81-8
Mol.F.	C12H9F3N2O2
Mol.Wt.	270.2
Inv. Status	In Stock

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Chemical Name: (Z)-2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide

Synonym: Leflunomide USP Related Compound B

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O/C(C)=C(C#N)\C(NC1=CC=C(C(F)(F)F)C=C1)=O

Isolation and characterization of a degradation product in leflunomide and a validated selective stability-indicating HPLC–UV method for their quantification
Balraj Saini and Gulshan Bansal
J Pharm Anal. 2015 Jun; 5(3): 207–212.

Rapid Stability Indicating HPLC Method for the Analysis of Leflunomide and Its Related Impurities in Bulk Drug and Formulations
Useni Reddy Mallu,1 Venkateswara Rao Anna,1 and Bikshal Babu Kasimala
Turk J Pharm Sci. 2019 Dec; 16(4): 457–465.

Leflunomide EP Impurity B is chemically (Z)-2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide. It is also known as Leflunomide USP Related Compound B. Leflunomide EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Leflunomide EP Impurity B

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