Haloperidol EP Impurity D

Spectrophotometric determination of haloperidol in pharmaceutical formulations
By Venkateswarlu, D.; Sreedevi, G.; Chakravarthy, I. E.; Rami Reddy, N.
From World Journal of Pharmaceutical Research (2020), 9(3), 764-769
 
Development and validation of RP-​HPLC method for the simultaneous estimation of haloperidol and trihexyphenidyl in API and combined tablet dosage form
By Amulya, E.; Kumar, N. Naveen; Mounika, CH.; Kowmudi, V.; Supriya, N.; Madhuri, K. Ramya
From International Journal of Applied Pharmaceutical Sciences and Research (2018), 3(3), 36-40

Haloperidol EP Impurity D is chemically 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-[4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]phenyl]butan-1-one (as per EP);4,4'-Bis[4-(p-chlorophenyl)-4-hydroxypiperidino]-butyrophenone (as per USP). It is also known as Haloperidol USP Related Compound A. Haloperidol EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Haloperidol EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Haloperidol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.