Gefitinib Impurity 27

SZ CAT No:	SZ-G018045
CAS No	692059-41-9
Mol.F.	C12H12Cl2N2O2
Mol.Wt.	287.1
Inv. Status	Custom Synthesis
Rel. CAS No	912556-90-2 (HCl salt)

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Chemical Name: 4-Chloro-6-(3-chloropropoxy)-7-methoxyquinazoline

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: ClC1=NC=NC2=CC(OC)=C(OCCCCl)C=C21

Identification, characterization and HPLC quantification of formulation-related impurities of honokiol, an antitumor natural drug candidate in clinical trials
Wenshuang Wu 1,2, # , Ming-Hai Tang2, # , Huan Tang 2 , Kai Chen 2,3 , Jie Fu 4 , Lun Wang 2,3 , Lin-Lin Xue 2 , Aihua Peng 2 , Haoyu Ye 2, 4* , Li-Juan Chen
Journal of Pharmaceutical and Biomedical Analysis Volume 153, 10 May 2018, Pages 186-192

Separation and Estimation of Process-Related Impurities of Gefitinib by Reverse-Phase High-Performance Liquid Chromatography
Karunakara A. Chandrashekara, Aparna Udupi, Chandrasekara G. Reddy
Journal of Chromatographic Science, Volume 52, Issue 8, September 2014, Pages 799–805

Gefitinib Impurity 27 is chemically 4-Chloro-6-(3-chloropropoxy)-7-methoxyquinazoline. Gefitinib Impurity 27 is supplied with detailed characterization data compliant with regulatory guideline. Gefitinib Impurity 27 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Gefitinib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Gefitinib EP Impurity A

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Gefitinib EP Impurity B

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Gefitinib N-Oxide

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Gefitinib 4-Desfluoro Impurity HCl

SZ CAT No:	: SZ-G018006
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O-Desmethyl Gefitinib

SZ CAT No:	: SZ-G018007
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3-Desmorpholinyl-3-Hydroxyethylamino Gefitinib

SZ CAT No:	: SZ-G018008
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Mol.F.	: C20H22ClFN4O3
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4-Defluoro-4-Hydroxy Gefitinib

SZ CAT No:	: SZ-G018009
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Mol.F.	: C22H25ClN4O4
Mol.Wt.	: 444.9
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N-(3-Morpholinopropyl) Gefitinib

SZ CAT No:	: SZ-G018010
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Mol.F.	: C29H37ClFN5O4 : 3(HCl)
Mol.Wt.	: 574.1 : 3(36.5)
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O-Desmorpholinopropyl-O-methyl Gefitinib

SZ CAT No:	: SZ-G018011
CAS No	: 153437-78-6
Mol.F.	: C16H13ClFN3O2
Mol.Wt.	: 333.8
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Gefitinib Impurity III

SZ CAT No:	: SZ-G018012
CAS No	: 95-76-1
Mol.F.	: C6H5Cl2N
Mol.Wt.	: 162
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Gefitinib Impurity IV HCl

SZ CAT No:	: SZ-G018013
CAS No	: NA
Mol.F.	: C22H24Cl2N4O3 : HCl
Mol.Wt.	: 463.4 : 36.5
Inv. Status	: In Stock
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Gefitinib Impurity V

SZ CAT No:	: SZ-G018014
CAS No	: 367-21-5
Mol.F.	: C6H5ClFN
Mol.Wt.	: 145.6
Inv. Status	: In Stock

Gefitinib Impurity VI

SZ CAT No:	: SZ-G018015
CAS No	: 7357-67-7
Mol.F.	: C7H14ClNO
Mol.Wt.	: 163.7
Inv. Status	: In Stock, 3-4 days for Dispatch

Gefitinib Impurity VII

SZ CAT No:	: SZ-G018016
CAS No	: 179688-53-0
Mol.F.	: C11H10N2O4
Mol.Wt.	: 234.2
Inv. Status	: In Stock

Gefitinib Impurity VIII

SZ CAT No:	: SZ-G018017
CAS No	: 788136-89-0
Mol.F.	: C17H13ClFN3O3
Mol.Wt.	: 361.8
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Gefitinib Impurity 1

SZ CAT No:	: SZ-G018018
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Mol.F.	: C15H23N3O4
Mol.Wt.	: 309.4
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Gefitinib Impurity 2

SZ CAT No:	: SZ-G018019
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Mol.F.	: C15H19N3O5
Mol.Wt.	: 321.3
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Gefitinib Impurity 3

SZ CAT No:	: SZ-G018020
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Mol.F.	: C15H22N2O5
Mol.Wt.	: 310.4
Inv. Status	: In Stock

Gefitinib Impurity 4

SZ CAT No:	: SZ-G018021
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Mol.F.	: C9H8N2O3
Mol.Wt.	: 192.2
Inv. Status	: In Stock

Gefitinib Impurity 6

SZ CAT No:	: SZ-G018023
CAS No	: 2475095-79-3
Mol.F.	: C16H19Cl2N3O3
Mol.Wt.	: 372.3
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Gefitinib Impurity 7

SZ CAT No:	: SZ-G018024
CAS No	: 2475095-82-8
Mol.F.	: C16H19Cl2N3O3
Mol.Wt.	: 372.3
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Gefitinib Impurity 8

SZ CAT No:	: SZ-G018025
CAS No	: 2512211-98-0
Mol.F.	: C17H12ClFN2O4
Mol.Wt.	: 362.7
Inv. Status	: Custom Synthesis

Gefitinib Impurity 9

SZ CAT No:	: SZ-G018026
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Mol.F.	: C22H23ClFN3O4
Mol.Wt.	: 447.9
Inv. Status	: Custom Synthesis

Gefitinib Impurity 10

SZ CAT No:	: SZ-G018027
CAS No	: 230955-75-6
Mol.F.	: C11H9ClN2O3
Mol.Wt.	: 252.7
Inv. Status	: In Stock

Gefitinib Impurity 11

SZ CAT No:	: SZ-G018028
CAS No	: NA
Mol.F.	: C21H20Cl3FN4O2
Mol.Wt.	: 485.8
Inv. Status	: Custom Synthesis

O-Desmorpholinopropyl Gefitinib

SZ CAT No:	: SZ-G018029
CAS No	: 184475-71-6
Mol.F.	: C15H11ClFN3O2
Mol.Wt.	: 319.7
Inv. Status	: In Stock

Gefitinib Impurity 13

SZ CAT No:	: SZ-G018030
CAS No	: 2254241-82-0
Mol.F.	: C22H25FN4O3
Mol.Wt.	: 412.5
Inv. Status	: Custom Synthesis

Gefitinib Impurity 14

SZ CAT No:	: SZ-G018031
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Mol.F.	: C16H20ClN3O3 : HCl
Mol.Wt.	: 337.8 : 36.5
Inv. Status	: In Stock
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3-Deschloro-3,4-Difluoro Gefitinib

SZ CAT No:	: SZ-G018032
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Mol.F.	: C22H24F2N4O3
Mol.Wt.	: 430.5
Inv. Status	: In Stock

Gefitinib D3

SZ CAT No:	: SZ-G018D01
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Gefitinib D8

SZ CAT No:	: SZ-G018D02
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Gefitinib Impurity 5

SZ CAT No:	: SZ-G018022
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Mol.F.	: C22H24ClFN4O3
Mol.Wt.	: 446.9
Inv. Status	: Custom Synthesis

Gefitinib Impurity 16

SZ CAT No:	: SZ-G018034
CAS No	: 350-30-1
Mol.F.	: C6H3ClFNO2
Mol.Wt.	: 175.5
Inv. Status	: Custom Synthesis

Gefitinib Impurity 19

SZ CAT No:	: SZ-G018037
CAS No	: 99-54-7
Mol.F.	: C6H3Cl2NO2
Mol.Wt.	: 192
Inv. Status	: Custom Synthesis

Gefitinib Impurity 21

SZ CAT No:	: SZ-G018039
CAS No	: 621-59-0
Mol.F.	: C8H8O3
Mol.Wt.	: 152.1
Inv. Status	: Custom Synthesis

Gefitinib Impurity 22

SZ CAT No:	: SZ-G018040
CAS No	: 934191-95-4
Mol.F.	: C15H22N2O4
Mol.Wt.	: 294.4
Inv. Status	: Custom Synthesis

Gefitinib Impurity 23

SZ CAT No:	: SZ-G018041
CAS No	: 675126-28-0
Mol.F.	: C15H20N2O3
Mol.Wt.	: 276.3
Inv. Status	: Custom Synthesis

Gefitinib Impurity 24

SZ CAT No:	: SZ-G018042
CAS No	: NA
Mol.F.	: C15H19N3O5
Mol.Wt.	: 321.3
Inv. Status	: Custom Synthesis

Gefitinib Impurity 26

SZ CAT No:	: SZ-G018044
CAS No	: 861453-11-4
Mol.F.	: C15H21NO4
Mol.Wt.	: 279.3
Inv. Status	: Custom Synthesis

Gefitinib Impurity 27

SZ CAT No:	: SZ-G018045
CAS No	: 692059-41-9
Mol.F.	: C12H12Cl2N2O2
Mol.Wt.	: 287.1
Inv. Status	: Custom Synthesis
Rel. CAS No	: 912556-90-2 (HCl salt)

Gefitinib Impurity 28

SZ CAT No:	: SZ-G018046
CAS No	: 912556-91-3
Mol.F.	: C18H16Cl2FN3O2
Mol.Wt.	: 396.2
Inv. Status	: Custom Synthesis

Gefitinib Nitroso Impurity

SZ CAT No:	: SZ-G018047
CAS No	: NA
Mol.F.	: C22H23ClFN5O4
Mol.Wt.	: 475.9
Inv. Status	: Inquire

Gefitinib Impurity 29

SZ CAT No:	: SZ-G018048
CAS No	: 578737-96-9
Mol.F.	: C22H24ClFN4O3
Mol.Wt.	: 446.9
Inv. Status	: Custom Synthesis
Rel. CAS No	: 944833-65-2 (HCl salt)

Gefitinib Impurity 30

SZ CAT No:	: SZ-G018049
CAS No	: 675126-27-9
Mol.F.	: C15H21N3O3
Mol.Wt.	: 291.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1561173-24-7 (HCl salt)

Gefitinib Impurity 31

SZ CAT No:	: SZ-G018050
CAS No	: 214472-37-4
Mol.F.	: C16H22N2O7
Mol.Wt.	: 354.4
Inv. Status	: Custom Synthesis

Gefitinib Impurity 32

SZ CAT No:	: SZ-G018051
CAS No	: 214472-41-0
Mol.F.	: C16H24N2O5
Mol.Wt.	: 324.4
Inv. Status	: Custom Synthesis

Gefitinib Impurity 33

SZ CAT No:	: SZ-G018052
CAS No	: 26791-93-5
Mol.F.	: C10H11NO6
Mol.Wt.	: 241.2
Inv. Status	: Custom Synthesis

Gefitinib Impurity 34

SZ CAT No:	: SZ-G018053
CAS No	: 31839-20-0
Mol.F.	: C8H7NO6
Mol.Wt.	: 213.1
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1024015-45-9 (potassium salt)

Gefitinib Impurity 35

SZ CAT No:	: SZ-G018054
CAS No	: 215659-03-3
Mol.F.	: C9H9NO6
Mol.Wt.	: 227.2
Inv. Status	: Custom Synthesis

Gefitinib Impurity 27

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