Fluorometholone Impurity 1

SZ CAT No:	SZ-F038002
CAS No	382-52-5
Mol.F.	C22H29FO5
Mol.Wt.	392.5
Inv. Status	In Stock

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Chemical Name: (6S,8S,9R,10S,11S,13S,14S,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

Synonym: Fluorometholone 21-Hydroxy Analog

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@]4(C)[C@](C(CO)=O)(O)CC[C@@]4([H])[C@]3([H])C[C@H](C)C2=C1

Validated HPTLC and HPLC methods for determination of fluorometholone and sodium cromoglycate in presence of their impurities and degradation products; application to kinetic study and on rabbit aqueous humor
Maha A. Hegazy, May H. Abdelwahab, Hassan A. M. Hendawy, Soheir A. Weshahy & Samah S. Abbas
Journal of Liquid Chromatography & Related Technologies Volume 41, 2018 - Issue 5 Pages 203-222

Hplc method for determination of fluorometholone and sodium cromoglycate in bulk and ophthalmic solution
Hani M. Hafez, Abdulla A. Elshanawany, Lobna M. Abdelaziz, Mustafa S. Mohram
J App Pharm Vol. 7; Issue 1: 01-08; January, 2015

Fluorometholone Impurity 1 is chemically (6S,8S,9R,10S,11S,13S,14S,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one. It is also known as Fluorometholone 21-Hydroxy Analog. Fluorometholone Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Fluorometholone Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fluorometholone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Fluorometholone Impurity 1

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