Felodipine D5

SZ CAT No:	SZ-F011D02
CAS No	1242281-38-4
Mol.F.	C18H14D5Cl2NO4
Mol.Wt.	389.3
Inv. Status	Custom Synthesis

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Chemical Name: 3-(Ethyl-d5) 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C(C(C(C=CC=C1Cl)=C1Cl)C(C(OC)=O)=C(C)N2)=C2C)OC([2H])([2H])C([2H])([2H])[2H]

Simultaneous determination of enalapril, felodipine and their degradation products in the dosage formulation by reversed-phase high-performance liquid chromatography using a Spherisorb C8 column
Xue-ZhiQinJoeDeMarcoDominic P.Ip
Journal of Chromatography A Volume 707, Issue 2, 21 July 1995, Pages 245-254

Characterizing the Impact of Hydroxypropylmethyl Cellulose on the Growth and Nucleation Kinetics of Felodipine from Supersaturated Solutions
David E. Alonzo,†,‡ Shweta Raina,† Deliang Zhou,§ Yi Gao,‡ Geoff G. Z. Zhang,*,‡ and Lynne S. Taylor
Cryst. Growth Des. 2012, 12, 3, 1538–1547

Stability Indicating Method for the Determination of Related Substances in Felodipine Solid Dosage Form and in the Drug Substance by RP-HPLC
Manoj Kumar Vadlamudi1,2 and Sangeetha Dhanaraj
Journal of Bioequivalence & Bioavailability Volume 8(4): 153-166 (2016)

Development and validation of UV spectrophotometric method for estimation of process related impurity in felodipine bulk and formulation
Vaibhav M. Thorat*1 , Pawar S. S.2 , Pande V. V.3 , Arote S. R.4 and Musmade Deepak S
Der Pharmacia Lettre, 2015, 7 (4):284-290

Quantitative analysis of the inhibitory effect of HPMC on felodipine crystallization kinetics using population balance modeling
Kaoutar Abbou Oucherif,*a Shweta Raina,b Lynne S. Taylorab and James D. Litster
CrystEngComm, 2013,15, 2197-2205

Felodipine D5 is chemically 3-(Ethyl-d5) 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate. Felodipine D5 is supplied with detailed characterization data compliant with regulatory guideline. Felodipine D5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Felodipine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Felodipine D5

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