Efinaconazole Impurity 21

SZ CAT No:	SZ-E027045
CAS No	NA
Mol.F.	C18H22F2N4O2
Mol.Wt.	364.4
Inv. Status	Custom Synthesis

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Chemical Name: (2R,3R)-2-(2,4-Difluorophenyl)-3-(1-oxa-6-azaspiro[2.5]octan-6-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: FC1=CC(F)=CC=C1[C@](CN2N=CN=C2)(O)[C@@H](C)N3CCC4(OC4)CC3

RP-HPLC-UV method development andvalidation for simultaneous determinationof terbutaline sulphate, ambroxol HCl andguaifenesin in pure and dosage forms
N. Itagimatha, D.H. Manjunatha
Annales Pharmaceutiques Françaises Volume 77, Issue 4, July 2019, Pages 295-301

A Facile Epoxide Aminolysis Promoted by (t-BuO)2Mg and Its Application to the Synthesis of Efinaconazole
Fuqiang Zhu, Yuanchao Xie, Jian Zhang, Guanghui Tian, Hongjian Qin, Xiaojun Yang, Tianwen Hu, Yang He, Haji Akber Aisa, and Jingshan Shen
Org. Process Res. Dev. 2018, 22, 5, 625–632

Efinaconazole Impurity 21 is chemically (2R,3R)-2-(2,4-Difluorophenyl)-3-(1-oxa-6-azaspiro[2.5]octan-6-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. Efinaconazole Impurity 21 is supplied with detailed characterization data compliant with regulatory guideline. Efinaconazole Impurity 21 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Efinaconazole.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-E027006
CAS No	: NA
Mol.F.	: C12H13F2N3O2 : CH4O3S
Mol.Wt.	: 269.3 : 96.1
Inv. Status	: In Stock
Rel. CAS No	: 135270-05-2 (free base)
Rel. CAT No	: SZ-E027040 ,

SZ CAT No:	: SZ-E027008
CAS No	: 144230-50-2
Mol.F.	: C6H11N : HCl
Mol.Wt.	: 97.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 148133-82-8 (free base)

SZ CAT No:	: SZ-E027011
CAS No	: 148133-82-8
Mol.F.	: C6H11N
Mol.Wt.	: 97.2
Inv. Status	: Out of Stock
Rel. CAS No	: 144230-50-2 (HCl salt)

SZ CAT No:	: SZ-E027014
CAS No	: 127000-90-2
Mol.F.	: C12H11F2N3O
Mol.Wt.	: 251.2
Inv. Status	: In Stock
Rel. CAS No	: 1216946-43-8 (HCl salt)

SZ CAT No:	: SZ-E027023
CAS No	: NA
Mol.F.	: C12H13F2N3O2 : CH4O3S
Mol.Wt.	: 269.3 : 96.1
Inv. Status	: In Stock
Rel. CAS No	: 2122222-14-2 (free base)

Efinaconazole Impurity 21

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SZ CAT No:	: SZ-E027001
CAS No	: 164650-44-6
Mol.F.	: C18H22F2N4O
Mol.Wt.	: 348.4
Inv. Status	: Out of Stock

SZ CAT No:	: SZ-E027002
CAS No	: 164650-45-7
Mol.F.	: C18H22F2N4O
Mol.Wt.	: 348.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027005
CAS No	: 135270-07-4
Mol.F.	: C12H11F2N3O
Mol.Wt.	: 251.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027007
CAS No	: 188904-84-9
Mol.F.	: C13H15NO
Mol.Wt.	: 201.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027009
CAS No	: 19980-00-8
Mol.F.	: C13H17NO2
Mol.Wt.	: 219.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027010
CAS No	: 133775-25-4
Mol.F.	: C12H13F2N3O2
Mol.Wt.	: 269.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027012
CAS No	: 2055038-61-2
Mol.F.	: C18H22F2N4O
Mol.Wt.	: 348.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027013
CAS No	: 2055038-60-1
Mol.F.	: C18H22F2N4O
Mol.Wt.	: 348.4
Inv. Status	: Out of Stock, Custom Synthesis

SZ CAT No:	: SZ-E027015
CAS No	: 135272-36-5
Mol.F.	: C12H13F2N3O2
Mol.Wt.	: 269.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027016
CAS No	: 135270-10-9
Mol.F.	: C18H22F2N4O
Mol.Wt.	: 348.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027017
CAS No	: 135270-13-2
Mol.F.	: C12H11F2N3O
Mol.Wt.	: 251.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027018
CAS No	: 135270-11-0
Mol.F.	: C12H13F2N3O2
Mol.Wt.	: 269.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027019
CAS No	: 2122222-10-8
Mol.F.	: C18H22F2N4O
Mol.Wt.	: 348.4
Inv. Status	: Limited Stock

SZ CAT No:	: SZ-E027020
CAS No	: NA
Mol.F.	: C12H11F2N3O
Mol.Wt.	: 251.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027021
CAS No	: NA
Mol.F.	: C18H22F2N4O
Mol.Wt.	: 348.4
Inv. Status	: Limited Stock

SZ CAT No:	: SZ-E027022
CAS No	: 2122222-15-3
Mol.F.	: C12H11F2N3O
Mol.Wt.	: 251.24
Inv. Status	: Out of Stock

SZ CAT No:	: SZ-E027024
CAS No	: NA
Mol.F.	: C12H13F2N3O2 : CH4O3S
Mol.Wt.	: 269.3 : 96.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027026
CAS No	: NA
Mol.F.	: C12H13F2N3O2
Mol.Wt.	: 269.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027027
CAS No	: 241479-72-1
Mol.F.	: C12H13F2N3O2
Mol.Wt.	: 269.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027028
CAS No	: 126918-16-9
Mol.F.	: C9H8F2O2
Mol.Wt.	: 186.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027029
CAS No	: 155137-12-5
Mol.F.	: C6H11N : HCl
Mol.Wt.	: 97.2 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 15031-81-9 (free base)

SZ CAT No:	: SZ-E027030
CAS No	: 159635-49-1
Mol.F.	: C11H19NO2
Mol.Wt.	: 197.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-E027031
CAS No	: NA
Mol.F.	: C18H23FN4O
Mol.Wt.	: 330.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027032
CAS No	: 2252350-11-9
Mol.F.	: C18H22FN4O : F
Mol.Wt.	: 329.4 : 19.0
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2252350-10-8 (free base)

SZ CAT No:	: SZ-E027033
CAS No	: NA
Mol.F.	: C18H22FN4O
Mol.Wt.	: 329.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027034
CAS No	: 2055038-64-5
Mol.F.	: C18H23FN4O
Mol.Wt.	: 330.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027035
CAS No	: 150803-08-0
Mol.F.	: C12H14FN3O2
Mol.Wt.	: 251.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-E027036
CAS No	: NA
Mol.F.	: C12H15N3O2
Mol.Wt.	: 233.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-E027037
CAS No	: 135133-23-2
Mol.F.	: C17H21F2N3O3
Mol.Wt.	: 353.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-E027038
CAS No	: 126918-17-0
Mol.F.	: C14H16F2O3
Mol.Wt.	: 270.3
Inv. Status	: In Stock