Efavirenz D5

SZ CAT No:	SZ-E003D01
CAS No	1132642-95-5
Mol.F.	C14H4D5ClF3NO2
Mol.Wt.	320.7
Inv. Status	Custom Synthesis

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Chemical Name: (S)-6-Chloro-4-((cyclopropyl-d5)ethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: FC(F)(F)[C@](C1=CC(Cl)=CC=C1NC2=O)(O2)C#CC3([2H])C([2H])([2H])C3([2H])[2H]

Development and validation of a HPLC analytical assay method for efavirenz tablets: a medicine for HIV infections
Osnir de Sá Viana1 , Flávia Patrícia Morais Medeiros2 , Severino Grangeiro-Júnior2 , Miracy Muniz Albuquerque1 , Mônica Felts La Roca Soares1-3, José Lamartine Soares-Sobrinho1-3, Lariza Darlene Santos Alves1 , Larissa Araújo Rolim1 , Keyla Emanuelle Ramos da Silva1 , Pedro José Rolim-Neto
Braz. J. Pharm. Sci. vol.47 no.1 São Paulo Jan./Mar. 2011

Investigation of the solvent-dependent photolysis of a nonnucleoside reverse-transcriptase inhibitor, antiviral agent efavirenz
Maryam A Jordaan and Michael Shapi
Antiviral Chemistry and Chemotherapy 2017: 1–11

Method Development and Validation for Related Impurities of Efavirenz by RP-HPLC Method
Desaraju Bhargavi, Bhukya Babu Rao, Gangarapu Kiran, Thumma Gouthami & Vasudha Bakshi
TACL 7 (5) 2017 pp 737 – 747

Efavirenz D5 is chemically (S)-6-Chloro-4-((cyclopropyl-d5)ethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one. Efavirenz D5 is supplied with detailed characterization data compliant with regulatory guideline. Efavirenz D5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Efavirenz.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-E003D03
CAS No	: NA
Mol.F.	: C14H5D4ClF3NO3
Mol.Wt.	: 335.7
Inv. Status	: Custom Synthesis
Rel. CAS No	: 205754-50-3 (Unlabeled)

SZ CAT No:	: SZ-E003D02
CAS No	: 1217771-47-5
Mol.F.	: C14H5D4ClF3NO3
Mol.Wt.	: 335.7
Inv. Status	: Custom Synthesis
Rel. CAS No	: 205754-33-2 (Unlabeled)

Efavirenz D5

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