Duloxetine D3

SZ CAT No:	SZ-D001D04
CAS No	919522-50-2
Mol.F.	C18H16D3NOS
Mol.Wt.	300.4
Inv. Status	Custom Synthesis

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Chemical Name: (S)-N-(Methyl-d3)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: [2H]C([2H])([2H])NCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C2C=CC=C3

Characterization of impurities formed by interaction of duloxetine HCl with enteric polymers hydroxypropyl methylcellulose acetate succinate and hydroxypropyl methylcellulose phthalate
P J Jansen 1, P L Oren, C A Kemp, S R Maple, S W Baertschi
J Pharm Sci. 1998 Jan;87(1):81-5.

Analysis of Duloxetine Hydrochloride and Its Related Compounds in Pharmaceutical Dosage Forms and In Vitro Dissolution Studies by Stability Indicating UPLC
Dantu Durga Rao1,*, Shakil S. Sait1, A. Malleswara Reddy1, Dinesh Chakole1, Y. Ramakoti Reddy2, and K. Mukkanti
Journal of Chromatographic Science, Vol. 48, November/December 2010

Development and validation of a stability indicating rp-lc method for the estimation of process related impurities and degradation products of duloxetine hydrochloride and phthalic acid in duloxetine hydrochloride delayed release capsules
Navneet Kumar,1,2 D. Sangeetha,2 Bhupendrasinh Vaghela,1 P. Sunil Reddy,1 and Anuj Raghav
Journal of Liquid Chromatography & Related Technologies, 35:867–881, 2012

Determinationof Duloxetine and Its MajorMetabolites in Rabbit Plasma by High-Performance Liquid Chromatography
T. K. Laha1*, S. Sen1, G. Mishra
International Journal of Pharmaceutical Sciences and Drug Research 2015; 7(2): 176-181

Development and Validation of UPLC Method for the Determination of Duloxetine Hydrochloride and Its Impurities in Active Pharmaceutical Ingredient
Rohith T1 , Ananda S1,2*, Sajan PG2 and Gowda NM3
J Anal Bioanal Tech Volume 6, Issue 1

Duloxetine D3 is chemically (S)-N-(Methyl-d3)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine. Duloxetine D3 is supplied with detailed characterization data compliant with regulatory guideline. Duloxetine D3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Duloxetine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-D001020
CAS No	: 2705426-23-7
Mol.F.	: C18H19NO2S : C2H4O2
Mol.Wt.	: 313.4 : 60.1
Inv. Status	: Custom Synthesis
Rel. CAS No	: 662149-13-5 (free base)

SZ CAT No:	: SZ-D001D03
CAS No	: NA
Mol.F.	: C24H21D6NO8S
Mol.Wt.	: 495.6
Inv. Status	: Custom Synthesis
Rel. CAS No	: 741693-83-4 (Unlabeled)

SZ CAT No:	: SZ-D001049
CAS No	: 116539-59-4
Mol.F.	: C18H19NOS
Mol.Wt.	: 297.4
Inv. Status	: Under Synthesis
Rel. CAS No	: 136434-34-9 (HCl salt) ; 116817-77-7 (Oxalate salt) ; 116817-86-8 (Maleate salt) ; 1106772-41-1 (HBr salt)

SZ CAT No:	: SZ-D001002
CAS No	: 910138-96-4
Mol.F.	: C18H19NOS : HCl
Mol.Wt.	: 297.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 116539-60-7 (free base)

SZ CAT No:	: SZ-D001004
CAS No	: 949095-98-1
Mol.F.	: C18H19NOS
Mol.Wt.	: 297.4
Inv. Status	: In Stock
Rel. CAS No	: 953028-76-7 (HCl salt) ; 949096-01-9 (HBr salt)

Duloxetine D3

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SZ CAT No:	: SZ-D001035
CAS No	: 134-32-7
Mol.F.	: C10H9N
Mol.Wt.	: 143.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001019
CAS No	: 732983-57-2
Mol.F.	: C19H21NO6S2
Mol.Wt.	: 423.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D001016
CAS No	: 1346599-09-4
Mol.F.	: C18H19NOS
Mol.Wt.	: 297.4
Inv. Status	: Out of Stock

SZ CAT No:	: SZ-D001052
CAS No	: NA
Mol.F.	: C25H23NO3S
Mol.Wt.	: 417.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D001D04
CAS No	: 919522-50-2
Mol.F.	: C18H16D3NOS
Mol.Wt.	: 300.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D001D01
CAS No	: 1276197-52-4
Mol.F.	: C18H14D5NOS
Mol.Wt.	: 302.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D001003
CAS No	: 116539-55-0
Mol.F.	: C8H13NOS
Mol.Wt.	: 171.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001005
CAS No	: 90-15-3
Mol.F.	: C10H8O
Mol.Wt.	: 144.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001006
CAS No	: 1033803-59-6
Mol.F.	: C18H19NOS
Mol.Wt.	: 297.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001007
CAS No	: 2379325-42-3
Mol.F.	: C18H19NOS : C2H2O4
Mol.Wt.	: 297.4 : 90.0
Inv. Status	: In Stock
Rel. CAS No	: 959392-22-4 (free base)
Rel. CAT No	: SZ-D001031 ,

SZ CAT No:	: SZ-D001008
CAS No	: 321-38-0
Mol.F.	: C10H7F
Mol.Wt.	: 146.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001001
CAS No	: 136434-34-9
Mol.F.	: C18H19NOS : HCl
Mol.Wt.	: 297.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 116539-59-4 (free base) ; 116817-77-7 (Oxalate salt) ; 116817-86-8 (Maleate salt) ; 1106772-41-1 (HBr salt)

SZ CAT No:	: SZ-D001022
CAS No	: 1243540-90-0
Mol.F.	: C20H21NO2S
Mol.Wt.	: 339.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001021
CAS No	: 1243540-89-7
Mol.F.	: C19H19NO2S
Mol.Wt.	: 325.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D001023
CAS No	: NA
Mol.F.	: C28H25NOS
Mol.Wt.	: 423.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D001033
CAS No	: 13196-35-5
Mol.F.	: C9H13NOS
Mol.Wt.	: 183.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001036
CAS No	: 603996-87-8
Mol.F.	: C8H11NO2S
Mol.Wt.	: 185.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001037
CAS No	: 603959-56-4
Mol.F.	: C8H11NO2S
Mol.Wt.	: 185.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D001038
CAS No	: 116817-12-0
Mol.F.	: C19H21NOS : C2H2O4
Mol.Wt.	: 311.4 : 90.0
Inv. Status	: In Stock
Rel. CAS No	: 116817-11-9 (free base)

SZ CAT No:	: SZ-D001039
CAS No	: 116817-14-2
Mol.F.	: C18H19NOS : C2H2O4
Mol.Wt.	: 297.4 : 90.0
Inv. Status	: In Stock
Rel. CAS No	: 116817-13-1 (free base) ; 947316-47-4 (HCl salt)
Rel. CAT No	: SZ-D001067 ,

SZ CAT No:	: SZ-D001041
CAS No	: 2418708-78-6
Mol.F.	: C8H12N2O2S
Mol.Wt.	: 200.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001043
CAS No	: 116539-56-1
Mol.F.	: C8H13NOS
Mol.Wt.	: 171.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001044
CAS No	: 1104890-90-5
Mol.F.	: C18H19NOS : HCl
Mol.Wt.	: 297.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 116817-27-7 (free base)

SZ CAT No:	: SZ-D001024
CAS No	: NA
Mol.F.	: C18H19NOS
Mol.Wt.	: 297.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D001045
CAS No	: NA
Mol.F.	: C8H12N2O2S
Mol.Wt.	: 200.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001048
CAS No	: 13636-02-7
Mol.F.	: C9H15NOS
Mol.Wt.	: 185.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001054
CAS No	: 132335-46-7
Mol.F.	: C19H21NOS
Mol.Wt.	: 311.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 132335-47-8 (oxalate salt) ; 1492053-96-9 (HCl salt)
Rel. CAT No	: SZ-D001025 ,

SZ CAT No:	: SZ-D001025
CAS No	: 132335-47-8
Mol.F.	: C19H21NOS : C2H2O4
Mol.Wt.	: 311.5 : 90.0
Inv. Status	: In Stock
Rel. CAS No	: 132335-46-7 (free base) ; 1492053-96-9 (HCl salt)
Rel. CAT No	: SZ-D001054 ,

SZ CAT No:	: SZ-D001026
CAS No	: 2230525-40-1
Mol.F.	: C8H13NOS
Mol.Wt.	: 171.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-D001027
CAS No	: 645411-16-1
Mol.F.	: C8H11NOS : HCl
Mol.Wt.	: 169.3 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 667465-15-8 (free base)