Doxycycline EP Impurity D

SZ CAT No:	SZ-D049005
CAS No	97583-08-9
Mol.F.	C22H24N2O8
Mol.Wt.	444.4
Inv. Status	Out of Stock, Custom Synthesis

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Chemical Name: (4R,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

Synonym: 4-Epi-6-epidoxycycline

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C1=C(O)[C@H](N(C)C)[C@@]([C@@H](O)[C@@]2([H])C(C(C3=C(O)C=CC=C3[C@H]2C)=O)=C4O)([H])[C@@]4(O)C1=O)N

Rapid liquid chromatographic method for the control of doxycycline and tiamulin residues and their metabolites in vivo assays with pigs: Treatment and depletion
By Cambeiro-Perez, Noelia; Gonzalez-Gomez, Xiana; Rey-Salgueiro, Ledicia; Simal-Gandara, Jesus; Martinez-Carballo, Elena
From Journal of Pharmaceutical and Biomedical Analysis (2020), 190, 113428

New HPLC-MS method for rapid and simultaneous quantification of doxycycline, diethylcarbamazine and albendazole metabolites in rat plasma and organs after concomitant oral administration
By Permana, Andi Dian; Tekko, Ismaiel A.; McCarthy, Helen O.; Donnelly, Ryan F.
From Journal of Pharmaceutical and Biomedical Analysis (2019), 170, 243-253

Doxycycline EP Impurity D is chemically (4R,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide. It is also known as 4-Epi-6-epidoxycycline. Doxycycline EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Doxycycline EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Doxycycline.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Doxycycline EP Impurity D

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