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Dexamethasone Phosphate

SZ CAT No SZ-D060023
CAS No 312-93-6
Mol.F. C22H30O8P
Mol.Wt. 472.4
Inv. Status Custom Synthesis
Rel. CAS No 2392-39-4 (sodium phosphate salt)


Chemical Name: 9-Fluoro-11β,17-dihydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate (as per EP); 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate) (as per USP)

Synonym: Dexamethasone 21-phosphate

Smiles: C[C@@]1([C@@]2(O)C(CO[P](O)(O)=O)=O)[C@](C[C@H]2C)([H])[C@@](CCC3=CC4=O)([H])[C@@](F)([C@]3(C=C4)C)[C@@H](O)C1

Inchi: InChI=1S/C8H14N2O5S/c9-4(7(12)13)1-2-6(11)10-5(3-16)8(14)15/h4-5,16H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5-/m0/s1

Stability and compatibility of methotrexate and dexamethasone in 0.9​% sodium chloride for intrathecal injection
By Xu, Fan; Zeng, Su
From Pakistan Journal of Pharmaceutical Sciences (2020), 33(6), 2477-2481
 
Method development and validation for simultaneous estimation of ofloxacin and dexamethasone sodium phosphate by RP-​HPLC
By Renukadevi, G. N.; Lakshmi, M. Sri; Prathyusha, V.; Sharmila, S. K.; Kumari, K. Shantha
From World Journal of Pharmaceutical Research (2014), 3(Suppl.5), 369-381
 
Simultaneous estimation of moxifloxacin hydrochloride and dexamethasone sodium phosphate in bulk and in ophthalmic solution by RP-​HPLC
By Dhumal, D. M.; Shirkhedkar, A. A.; Nerkar, P. P.; Surana, S. J.
From Journal of the Chilean Chemical Society (2012), 57(4), 1344-1347