Dexamethasone EP Impurity B

SZ CAT No:	SZ-D024003
CAS No	378-44-9
Mol.F.	C22H29FO5
Mol.Wt.	392.5
Inv. Status	In Stock
Rel. CAS No	7460-03-9 (Na salt) ; 956901-32-9 (HCl salt)

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Chemical Name: 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione (as per EP)

Synonym: Betamethasone (EP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: F[C@@]1([C@]2(C=C3)C)[C@](CCC2=CC3=O)([H])[C@@](C[C@H](C)[C@]4(O)C(CO)=O)([H])[C@]4(C)C[C@@H]1O

Stability and compatibility of methotrexate and dexamethasone in 0.9% sodium chloride for intrathecal injection
By Xu, Fan; Zeng, Su
From Pakistan Journal of Pharmaceutical Sciences (2020), 33(6), 2477-2481

Stability indicating RP-HPLC method development and validation for dexamethasone
By Kulkarni, Pankaj N.; Jadhav, C. K.; Nipate, A. S.; Dodake-Supekar, Alaknanda M.; Gill, C. H.
From Asian Journal of Chemistry (2020), 32(3), 587-591

Dexamethasone EP Impurity B is chemically 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione (as per EP). It is also known as Betamethasone (EP). Dexamethasone EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Dexamethasone EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dexamethasone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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