Desmethyl Thiosildenafil D8

SZ CAT No:	SZ-S006D06
CAS No	1215321-44-0
Mol.F.	C21H20D8N6O3S2
Mol.Wt.	484.7
Inv. Status	Custom Synthesis

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Chemical Name: 5-(2-Ethoxy-5-((piperazin-1-yl-2,2,3,3,5,5,6,6-d8)sulfonyl)phenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-thione

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CCCC1=NN(C)C2=C1NC(C(C=C([S](=O)(N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])=O)C=C4)=C4OCC)=NC2=S

Quantification of active pharmaceutical ingredient and impurities in sildenafil citrate obtained from the Internet
Michael A Veronin , Mohammad T Nutan , Uday Krishna Reddy Dodla
Ther Adv Drug Saf. 2014 Oct;5(5):180-9

Validated Methods for Determination of Sildenafil Citrate in The Presence of its Potential Impurities
A.E. El-Gindy , E. Shokry M. Farouk , L. Abd El-Aziz
J Biomed Sci and Res., Vol 2 (4), 2010,262-278

Validated LC method for sildenafil citrate related substances and its potential oxidative degradation product
A.Nageswari, P.Surya Prakash Rao, B.Gowri Sankar Rao, B.Satyanarayana , M.Saravanan , V.Ranga Reddy , Mukkanti
ACAIJ, 10(10) 2011 [683-690]

Determinaton of sildenafil citrate and related substances in the commercial products and tablet dosage form using HPLC
N Daraghmeh, M Al-Omari, A.ABadwan, A.M.YJaber
Journal of Pharmaceutical and Biomedical Analysis Volume 25, Issues 3–4, June 2001, Pages 483-492

Desmethyl Thiosildenafil D8 is chemically 5-(2-Ethoxy-5-((piperazin-1-yl-2,2,3,3,5,5,6,6-d8)sulfonyl)phenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-thione. Desmethyl Thiosildenafil D8 is supplied with detailed characterization data compliant with regulatory guideline. Desmethyl Thiosildenafil D8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Sildenafil .

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-S006000
CAS No	: 139755-83-2
Mol.F.	: C22H30N6O4S
Mol.Wt.	: 474.6
Inv. Status	: In Stock
Rel. CAS No	: 171599-83-0 (citrate salt)

SZ CAT No:	: SZ-S006033
CAS No	: 288-32-4
Mol.F.	: C3H4N2
Mol.Wt.	: 68.1
Inv. Status	: In Stock
Rel. CAT No	: SZ-B079004 , SZ-C001003 , SZ-E011010 , SZ-Z005021 ,

SZ CAT No:	: SZ-S006036
CAS No	: 171599-83-0
Mol.F.	: C22H30N6O4S : C6H8O7
Mol.Wt.	: 474.6 : 192.1
Inv. Status	: In Stock
Rel. CAS No	: 139755-83-2 (free base)

Desmethyl Thiosildenafil D8

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SZ CAT No:	: SZ-S006002
CAS No	: 1391053-95-4
Mol.F.	: C23H32N6O4S
Mol.Wt.	: 488.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-S006003
CAS No	: 1094598-75-0
Mol.F.	: C22H30N6O5S
Mol.Wt.	: 490.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-S006004
CAS No	: 139755-91-2
Mol.F.	: C20H26N6O4S
Mol.Wt.	: 446.5
Inv. Status	: Out of Stock, Custom Synthesis

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CAS No	: 1357931-55-5
Mol.F.	: C17H20N4O5S
Mol.Wt.	: 392.4
Inv. Status	: In Stock

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Mol.F.	: C9H9ClO2
Mol.Wt.	: 184.6
Inv. Status	: In Stock

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Mol.F.	: C8H14N4O
Mol.Wt.	: 182.2
Inv. Status	: In Stock

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CAS No	: 147676-78-6
Mol.F.	: C18H20N4O4
Mol.Wt.	: 356.4
Inv. Status	: Custom Synthesis

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CAS No	: 1058653-74-9
Mol.F.	: C19H21ClN4O3
Mol.Wt.	: 388.9
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-S006010
CAS No	: 501120-42-9
Mol.F.	: C17H19ClN4O4S
Mol.Wt.	: 410.9
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-S006011
CAS No	: 139756-22-2
Mol.F.	: C17H19ClN4O4S
Mol.Wt.	: 410.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-S006012
CAS No	: 139756-27-7
Mol.F.	: C15H15ClN4O4S
Mol.Wt.	: 382.8
Inv. Status	: Custom Synthesis

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CAS No	: 139756-31-3
Mol.F.	: C16H17ClN4O4S
Mol.Wt.	: 396.9
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-S006014
CAS No	: 466684-88-8
Mol.F.	: C20H28N6O4S
Mol.Wt.	: 448.5
Inv. Status	: Custom Synthesis

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CAS No	: 139756-03-9
Mol.F.	: C17H22N4O3
Mol.Wt.	: 330.4
Inv. Status	: In Stock

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Mol.F.	: C38H46N10O8S2
Mol.Wt.	: 835.0
Inv. Status	: In Stock

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CAS No	: 1346600-82-5
Mol.F.	: C9H12N4
Mol.Wt.	: 176.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-S006018
CAS No	: 139756-21-1
Mol.F.	: C17H20N4O2
Mol.Wt.	: 312.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-S006019
CAS No	: 139755-82-1
Mol.F.	: C21H28N6O4S
Mol.Wt.	: 460.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-S006020
CAS No	: 479073-86-4
Mol.F.	: C21H28N6O3S2
Mol.Wt.	: 476.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-S006021
CAS No	: 501120-38-3
Mol.F.	: C17H22N4O3
Mol.Wt.	: 330.4
Inv. Status	: In Stock

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CAS No	: 1004455-71-3
Mol.F.	: C9H13N3O4
Mol.Wt.	: 227.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-S006023
CAS No	: 1467610-65-6
Mol.F.	: C18H22N4O2
Mol.Wt.	: 326.4
Inv. Status	: In Stock

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CAS No	: 253178-46-0
Mol.F.	: C22H30N6O4S
Mol.Wt.	: 474.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-S006025
CAS No	: 911715-34-9
Mol.F.	: C9H14N4O3
Mol.Wt.	: 226.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-S006026
CAS No	: 247583-78-4
Mol.F.	: C8H14N4O
Mol.Wt.	: 182.2
Inv. Status	: In Stock

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CAS No	: 268204-00-8
Mol.F.	: C9H16N4O
Mol.Wt.	: 196.3
Inv. Status	: In Stock

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CAS No	: 247583-72-8
Mol.F.	: C8H12N4O3
Mol.Wt.	: 212.2
Inv. Status	: In Stock

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CAS No	: 139756-00-6
Mol.F.	: C8H11N3O4
Mol.Wt.	: 213.2
Inv. Status	: In Stock

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CAS No	: 139756-01-7
Mol.F.	: C8H12N4O3
Mol.Wt.	: 212.2
Inv. Status	: In Stock

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Mol.F.	: C9H10O3
Mol.Wt.	: 166.2
Inv. Status	: In Stock