Darifenacin Impurity E

SZ CAT No:	SZ-D004027
CAS No	1797983-04-0
Mol.F.	C38H40N2O3
Mol.Wt.	572.7
Inv. Status	Out of Stock

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Chemical Name: 4-(2-(Bis(2-(2,3-dihydrobenzofuran-5-yl)ethyl)amino)ethyl)-3,3-diphenylpyrrolidin-2-one

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(CN1)CCN(CCC4=CC=C(OCC5)C5=C4)CCC6=CC=C(OCC7)C7=C6

Identification, isolation and characterization of dimer impurities in antimuscarinic agent darifenacin hydrobromide
By Gupta, P. Badarinadh; Rao, B. Venkateswara; Douglas, S. Paul; Sharma, Hemant Kumar; Bharathi, D. Vijaya
From World Journal of Pharmaceutical Research (2017), 6(6), 1041-1063

Development and validation of HPLC method for determination of potential genotoxic impurities in darifenacin hydrobromide drug substance
By Patcha, Vinay Kumar; Gajbhiye, Susheela Bhai; Vundavilli, Jagadeesh Kumar; Kothapalli, S. R. Pavan Kumar; Sreenivas, N.; Ray, U. K.
From International Journal of Pharmacy and Pharmaceutical Research (2017), 8(2), 198-208

Development and validation of a stability-indicating RP-HPLC method for determination of darifenacin hydrobromide in bulk drugs
By Nazeerunnisa, Mohammed; Garikapati, Lakshmi; Bethanabhatla, Syama Sundar
From American Journal of Analytical Chemistry (2014), 5(17), 1239-1248

Darifenacin Impurity E is chemically 4-(2-(Bis(2-(2,3-dihydrobenzofuran-5-yl)ethyl)amino)ethyl)-3,3-diphenylpyrrolidin-2-one. Darifenacin Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Darifenacin Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darifenacin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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SZ CAT No:	: SZ-D004004
CAS No	: 206048-82-0
Mol.F.	: C28H30N2O3
Mol.Wt.	: 442.6
Inv. Status	: Custom Synthesis

Darifenacin 4-Hydroxy Impurity

SZ CAT No:	: SZ-D004016
CAS No	: 2468796-89-4
Mol.F.	: C28H31BrN2O2
Mol.Wt.	: 507.5
Inv. Status	: Out of Stock, Custom Synthesis
Rel. CAS No	: 2468796-90-7 (HBr salt)

Darifenacin 5-Carboxymethyl Impurity

SZ CAT No:	: SZ-D004006
CAS No	: 69999-16-2
Mol.F.	: C10H10O3
Mol.Wt.	: 178.2
Inv. Status	: In Stock

Darifenacin 7-Bromo Analog

SZ CAT No:	: SZ-D004017
CAS No	: 1391080-43-5
Mol.F.	: C28H29BrN2O2
Mol.Wt.	: 505.5
Inv. Status	: In Stock

Darifenacin 7-Bromoethyl Impurity

SZ CAT No:	: SZ-D004018
CAS No	: 1598271-92-1
Mol.F.	: C10H11BrO
Mol.Wt.	: 227.1
Inv. Status	: Out of Stock, Custom Synthesis

Darifenacin Bromo Impurity

SZ CAT No:	: SZ-D004005
CAS No	: 127264-14-6
Mol.F.	: C10H11BrO
Mol.Wt.	: 227.1
Inv. Status	: In Stock

Darifenacin Carboxylic Acid Impurity

SZ CAT No:	: SZ-D004019
CAS No	: 1048979-16-3
Mol.F.	: C28H29NO3
Mol.Wt.	: 427.5
Inv. Status	: Out of Stock, Custom Synthesis

Darifenacin Cyano Pyrrolidine Impurity

SZ CAT No:	: SZ-D004007
CAS No	: 871505-23-6
Mol.F.	: C18H18N2 : HCl
Mol.Wt.	: 262.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 133099-11-3 (Free base) ; 1207849-19-1 (Oxalate salt)

Darifenacin Cyano t-BOC Impurity

SZ CAT No:	: SZ-D004014
CAS No	: 1159977-31-7
Mol.F.	: C23H26N2O2
Mol.Wt.	: 362.5
Inv. Status	: In Stock

Darifenacin D4

SZ CAT No:	: SZ-D004D01
CAS No	: 1095598-84-7
Mol.F.	: C28H26D4N2O2
Mol.Wt.	: 430.6
Inv. Status	: Custom Synthesis

Darifenacin DBE Isomer

SZ CAT No:	: SZ-D004008
CAS No	: NA
Mol.F.	: C28H30N2O2
Mol.Wt.	: 426.6
Inv. Status	: Custom Synthesis

Darifenacin Dimer-1 Impurity

SZ CAT No:	: SZ-D004010
CAS No	: NA
Mol.F.	: C38H40N2O3
Mol.Wt.	: 572.7
Inv. Status	: Custom Synthesis

Darifenacin Dimer-2 Impurity

SZ CAT No:	: SZ-D004011
CAS No	: 2280857-32-9
Mol.F.	: C38H40N2O3
Mol.Wt.	: 572.7
Inv. Status	: In Stock

Darifenacin Hydrobromide

SZ CAT No:	: SZ-D004001
CAS No	: 133099-07-7
Mol.F.	: C28H30N2O2 : HBr
Mol.Wt.	: 426.6 : 80.9
Inv. Status	: In Stock
Rel. CAS No	: 133099-04-4 (Free base)

Darifenacin Impurity (UK-156961)

SZ CAT No:	: SZ-D004024
CAS No	: 206048-83-1
Mol.F.	: C28H32N2O3
Mol.Wt.	: 444.6
Inv. Status	: Custom Synthesis

Darifenacin Impurity 1

SZ CAT No:	: SZ-D004033
CAS No	: 133099-09-9
Mol.F.	: C25H24N2O2S
Mol.Wt.	: 416.6
Inv. Status	: In Stock

Darifenacin Impurity 10 (Tartrate salt)

SZ CAT No:	: SZ-D004047
CAS No	: 1092540-94-7
Mol.F.	: C18H20N2O : C4H6O6
Mol.Wt.	: 280.4 : 150.1
Inv. Status	: In Stock
Rel. CAS No	: 134002-27-0 (Free base)

Darifenacin Impurity 11

SZ CAT No:	: SZ-D004068
CAS No	: 1229355-35-4
Mol.F.	: C18H18N2 : HBr
Mol.Wt.	: 262.4 : 80.9
Inv. Status	: In Stock
Rel. CAS No	: 133099-12-4 (free base)

Darifenacin Impurity 11

SZ CAT No:	: SZ-D004048
CAS No	: 1048979-15-2
Mol.F.	: C27H29NO
Mol.Wt.	: 383.5
Inv. Status	: In Stock

Darifenacin Impurity 12

SZ CAT No:	: SZ-D004049
CAS No	: NA
Mol.F.	: C27H29NO
Mol.Wt.	: 383.5
Inv. Status	: In Stock

Darifenacin Impurity 12

SZ CAT No:	: SZ-D004069
CAS No	: NA
Mol.F.	: C28H28N2O : HBr
Mol.Wt.	: 408.5 : 80.9
Inv. Status	: Custom Synthesis

Darifenacin Impurity 13

SZ CAT No:	: SZ-D004052
CAS No	: NA
Mol.F.	: C46H46N4O4
Mol.Wt.	: 718.9
Inv. Status	: Custom Synthesis

Darifenacin Impurity 2

SZ CAT No:	: SZ-D004034
CAS No	: 133099-10-2
Mol.F.	: C25H24N2O2S
Mol.Wt.	: 416.6
Inv. Status	: Custom Synthesis

Darifenacin Impurity 3

SZ CAT No:	: SZ-D004037
CAS No	: 86-29-3
Mol.F.	: C14H11N
Mol.Wt.	: 193.3
Inv. Status	: In Stock

Darifenacin Impurity 5

SZ CAT No:	: SZ-D004038
CAS No	: NA
Mol.F.	: C20H22O6S2
Mol.Wt.	: 422.5
Inv. Status	: Custom Synthesis

Darifenacin Impurity 6

SZ CAT No:	: SZ-D004039
CAS No	: 133034-07-8
Mol.F.	: C28H28N2O3
Mol.Wt.	: 440.6
Inv. Status	: In Stock
Rel. CAS No	: 133034-08-9 (HCl salt)

Darifenacin Impurity 7

SZ CAT No:	: SZ-D004040
CAS No	: NA
Mol.F.	: C19H22N2O
Mol.Wt.	: 294.4
Inv. Status	: Custom Synthesis

Darifenacin Impurity 8

SZ CAT No:	: SZ-D004044
CAS No	: 87776-76-9
Mol.F.	: C10H12O2
Mol.Wt.	: 164.2
Inv. Status	: In Stock

Darifenacin Impurity 9

SZ CAT No:	: SZ-D004046
CAS No	: 142935-60-2
Mol.F.	: C10H8O3
Mol.Wt.	: 176.2
Inv. Status	: In Stock

Darifenacin Impurity B

SZ CAT No:	: SZ-D004045
CAS No	: 136081-60-2
Mol.F.	: C11H14O4S
Mol.Wt.	: 242.3
Inv. Status	: Out of Stock

Darifenacin Impurity E

SZ CAT No:	: SZ-D004027
CAS No	: 1797983-04-0
Mol.F.	: C38H40N2O3
Mol.Wt.	: 572.7
Inv. Status	: Out of Stock

Darifenacin Impurity H

SZ CAT No:	: SZ-D004028
CAS No	: NA
Mol.F.	: C47H50N4O3
Mol.Wt.	: 718.9
Inv. Status	: In Stock

Darifenacin KSM-I A

SZ CAT No:	: SZ-D004041
CAS No	: 90843-31-5
Mol.F.	: C10H10O2
Mol.Wt.	: 162.2
Inv. Status	: In Stock

Darifenacin KSM-II B Precursor

SZ CAT No:	: SZ-D004042
CAS No	: 133034-01-2
Mol.F.	: C18H21NO5S2
Mol.Wt.	: 395.5
Inv. Status	: Custom Synthesis

Darifenacin KSM-II C Precursor

SZ CAT No:	: SZ-D004043
CAS No	: 943587-25-5
Mol.F.	: C11H15NO3S
Mol.Wt.	: 241.3
Inv. Status	: Custom Synthesis

Darifenacin Morpholine Amide Impurity

SZ CAT No:	: SZ-D004035
CAS No	: 97483-11-9
Mol.F.	: C14H17NO2S
Mol.Wt.	: 263.4
Inv. Status	: In Stock

Darifenacin Nitrile Impurity (HCl)

SZ CAT No:	: SZ-D004012
CAS No	: NA
Mol.F.	: C28H28N2O : HCl
Mol.Wt.	: 408.5 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 252317-48-9 (free base) ; 608127-89-5 (HBr salt)

Darifenacin Nitroso Impurity 1

SZ CAT No:	: SZ-D004070
CAS No	: NA
Mol.F.	: C18H19N3O2
Mol.Wt.	: 309.4
Inv. Status	: Custom Synthesis

Darifenacin N-Oxide Impurity

SZ CAT No:	: SZ-D004020
CAS No	: 1391080-40-2
Mol.F.	: C28H30N2O3
Mol.Wt.	: 442.6
Inv. Status	: In Stock

Darifenacin Oxidized Impurity

SZ CAT No:	: SZ-D004026
CAS No	: 133033-99-5
Mol.F.	: C28H28N2O2
Mol.Wt.	: 424.5
Inv. Status	: In Stock
Rel. CAS No	: 943034-52-4 (HBr salt)

Darifenacin Pyrrolidin Carboxylic Acid Impurity

SZ CAT No:	: SZ-D004021
CAS No	: 1050646-75-7
Mol.F.	: C18H19NO2
Mol.Wt.	: 281.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1415566-36-7 (HBr salt)

Darifenacin Pyrrolidine Impurity (S)-Isomer

SZ CAT No:	: SZ-D004003
CAS No	: 134002-26-9
Mol.F.	: C18H20N2O : C4H6O6
Mol.Wt.	: 280.4 : 150.1
Inv. Status	: In Stock
Rel. CAS No	: 134002-25-8 (Free base)

Darifenacin Pyrrolidine Impurity Racemate

SZ CAT No:	: SZ-D004013
CAS No	: 103887-32-7
Mol.F.	: C18H20N2O
Mol.Wt.	: 280.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 103913-15-1 (HCl salt) ; 1092540-81-2 (HBr salt)

Darifenacin Pyrrolidinium Dimer Impurity

SZ CAT No:	: SZ-D004022
CAS No	: 1396968-57-2
Mol.F.	: C38H41N2O3 : Br
Mol.Wt.	: 573.8 : 79.9
Inv. Status	: In Stock
Rel. CAS No	: 1397321-17-3 (Free base)

Darifenacin Recemic Mixture

SZ CAT No:	: SZ-D004054
CAS No	: 133033-93-9
Mol.F.	: C28H30N2O2
Mol.Wt.	: 426.6
Inv. Status	: Out of Stock
Rel. CAS No	: 1092540-82-3 (HBr salt)

Darifenacin R-Isomer (HCl)

SZ CAT No:	: SZ-D004002
CAS No	: NA
Mol.F.	: C28H30N2O2 : HCl
Mol.Wt.	: 426.6 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 133099-05-5 (free base)

Darifenacin Vinyl Impurity (UK-201705)

SZ CAT No:	: SZ-D004029
CAS No	: 1048979-09-4
Mol.F.	: C28H30N2O2
Mol.Wt.	: 426.6
Inv. Status	: In Stock

Darifenacin Vinylbenzofuran Impurity

SZ CAT No:	: SZ-D004023
CAS No	: 633335-98-5
Mol.F.	: C10H8O
Mol.Wt.	: 144.2
Inv. Status	: Custom Synthesis

Darifenacin Impurity E

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