Cloxacillin EP Impurity E

SZ CAT No:	SZ-C084006
CAS No	NA
Mol.F.	C27H28ClN5O7S2
Mol.Wt.	634.1
Inv. Status	In Stock

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Chemical Name: (2S,5R,6R)-6-[[[(2S,5R,6R)-6-[[[3-(2-Chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Synonym: 6-APA Cloxacillin Amide

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@@H](C(C)(C)S[C@]3([H])[C@@H]4NC(C5=C(C)ON=C5C6=CC=CC=C6Cl)=O)N3C4=O)=O)N1C2=O)O

Application of quality by design concept to develop a dual gradient elution stability-indicating method for cloxacillin forced degradation studies using combined mixture-process variable models
XiaZhangChangqinHu
Journal of Chromatography A Volume 1514, 8 September 2017, Pages 44-53

Analysis of Ampicillin, Cloxacillin and Their Related Substances in Capsules, Syrups and Suspensions by High-performance Liquid Chromatography
Omar Shakoor and Robert B. Taylor
Analyst, Octohei- 1996, Vol. I21 (1473-1477)

Photoelectrochemical impedance spectroscopy sensor for cloxacillin based on tetrabutylammonium octamolybdate
D. Najlaoui1 & M. Echabaane2 & A. Ben Khélifa3 & A. Rouis1 & H. Ben Ouada1
Journal of Solid State Electrochemistry volume 23, pages3329–3341(2019)

Cloxacillin EP Impurity E is chemically (2S,5R,6R)-6-[[[(2S,5R,6R)-6-[[[3-(2-Chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. It is also known as 6-APA Cloxacillin Amide. Cloxacillin EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Cloxacillin EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cloxacillin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Cloxacillin EP Impurity E

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