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Clopidogrel Impurity B

SZ CAT No SZ-C044016
CAS No 402746-56-9
Mol.F. C15H16ClNO2S : H2O4S
Mol.Wt. 309.8 : 98.1
Inv. Status Custom Synthesis
Rel. CAS No 141109-26-4 (free base) ; 141109-18-4 (HCl salt) ; 216249-54-6 (HBr salt)


Chemical Name: Methyl 2-(2-chlorophenyl)-2-((2-(thiophen-2-yl)ethyl)amino)acetate sulfate

Smiles: ClC1=C(C(C(OC)=O)NCCC2=CC=CS2)C=CC=C1.O=[S](O)(O)=O

Inchi: InChI=1S/C28H31N3O6.ClH/c1-18-24(27(32)36-3)26(21-11-7-12-22(15-21)31(34)35)25(19(2)29-18)28(33)37-23-13-8-14-30(17-23)16-20-9-5-4-6-10-20;/h4-7,9-12,15,23,26,29H,8,13-14,16-17H2,1-3H3;1H/t23-,26+;/m1./s1

Separation and determination of clopidogrel and its impurities by capillary electrophoresis
Ahmed S. Fayeda,b,∗, Soheir A. Weshahy b, Mostafa A. Shehata b, Nagiba Y. Hassanb, Jochen Pauwels a, Jos Hoogmartens a, Ann Van Schepdael
Journal of Pharmaceutical and Biomedical Analysis 49 (2009) 193–200
 
Identification and characterization of a principal oxidation impurity in clopidogrel drug substance and drug product
Arivozhi Mohan ∗, M. Hariharan a, E. Vikraman a, G. Subbaiah a, B.R. Venkataraman b, D. Saravanan
Journal of Pharmaceutical and Biomedical Analysis 47 (2008) 183–189
 
The Efficacy and Safety of Clopidogrel Resinate as A Novel Polymeric Salt Form of Clopidogrel
Min-Hyo Ki, Mee-Hwa Choi, Kwang-Bok Ahn, Byoung-Su Kim, Dai Sig Im1 , Soon-Kil Ahn1 , and Hee-Jong Shin
Arch Pharm Res Vol 31, No 2, 250-258, 2008
 
New and Efficient Synthetic Approaches for the Regioisomeric and Iminium Impurities of Clopidogrel Bisulfate
Sampath Aalla,‡ Goverdhan Gilla,*,‡ Raghupathi Reddy Anumula,‡ Kavitha Charagondla,‡ Prabhakar Reddy Vummenthala,§ and Pratap Reddy Padi
rg. Process Res. Dev. 2012, 16, 9, 1523–1526