Cinacalcet 7,8-Dihydro Racemate Base

SZ CAT No:	SZ-C036013
CAS No	802918-46-3
Mol.F.	C22H24F3N
Mol.Wt.	359.4
Inv. Status	Custom Synthesis

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Chemical Name: 7,8-Dihydro-α-methyl-N-[3-[3- (trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CC(NCCCC1=CC(C(F)(F)F)=CC=C1)C2=CC=CC3=C2CCC=C3

Chiral capillary zone electrophoresis in enantioseparation and analysis of cinacalcet impurities: Use of Quality by Design principles in method development
Benedetta Pasquini a, Serena Orlandini a,∗, Mercedes Villar-Navarro b, Claudia Caprini a, Massimo Del Bubbaa, Michal Dousaˇ c, Alessandro Giuffrida d, Roberto Gotti e, Sandra Furlanetto
Journal of Chromatography A Volume 1568, 21 September 2018, Pages 205-213

Development and Validation of a Stability-Indicating RP-UPLC Method for the Estimation of Impurities in Cinacalcet Hydrochloride API and its Formulation
Pingili Sunil reddy, Thummala Veera Raghava Raju , Penmetsa Satyanarayana RAJU , Nadimpalli Sunil Varma 1 , Kondra Sudhakar BABU
Sci. Pharm. 2015, 83(4), 583-598

Cinacalcet 7,8-Dihydro Racemate Base is chemically 7,8-Dihydro-α-methyl-N-[3-[3- (trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine. Cinacalcet 7,8-Dihydro Racemate Base is supplied with detailed characterization data compliant with regulatory guideline. Cinacalcet 7,8-Dihydro Racemate Base can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cinacalcet.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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SZ CAT No:	: SZ-C036016
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Mol.F.	: C10H15NO : HCl
Mol.Wt.	: 165.2 : 36.5
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Cinacalcet 5,6-Dihydro Racemate Base

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Cinacalcet 7,8-Dihydro Racemate Base

SZ CAT No:	: SZ-C036013
CAS No	: 802918-46-3
Mol.F.	: C22H24F3N
Mol.Wt.	: 359.4
Inv. Status	: Custom Synthesis

Cinacalcet D3

SZ CAT No:	: SZ-C036D01
CAS No	: 1228567-12-1
Mol.F.	: C22H19D3F3N
Mol.Wt.	: 360.4
Inv. Status	: Custom Synthesis

Cinacalcet D4

SZ CAT No:	: SZ-C036D02
CAS No	: 1228567-29-0
Mol.F.	: C22H18D4F3N
Mol.Wt.	: 361.4
Inv. Status	: Custom Synthesis

Cinacalcet HCl

SZ CAT No:	: SZ-C036001
CAS No	: 364782-34-3
Mol.F.	: C22H22F3N : HCl
Mol.Wt.	: 357.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 226256-56-0 (free base)

Cinacalcet Hydroxy Impurity

SZ CAT No:	: SZ-C036034
CAS No	: NA
Mol.F.	: C21H24F3NO
Mol.Wt.	: 363.4
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 1

SZ CAT No:	: SZ-C036017
CAS No	: 104774-93-8
Mol.F.	: C10H12F3N : HCl
Mol.Wt.	: 203.2 : 36.5
Inv. Status	: Limited Stock
Rel. CAS No	: 104774-87-0 (free base)

Cinacalcet Impurity 10

SZ CAT No:	: SZ-C036026
CAS No	: 123486-66-8
Mol.F.	: C10H7F3O
Mol.Wt.	: 200.2
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 11

SZ CAT No:	: SZ-C036027
CAS No	: 254437-97-3
Mol.F.	: C13H15N
Mol.Wt.	: 185.3
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 12

SZ CAT No:	: SZ-C036028
CAS No	: 254437-90-6
Mol.F.	: C13H15N
Mol.Wt.	: 185.3
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 13

SZ CAT No:	: SZ-C036029
CAS No	: 1956-40-7
Mol.F.	: C12H11NO
Mol.Wt.	: 185.2
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 14

SZ CAT No:	: SZ-C036030
CAS No	: 1224568-02-8
Mol.F.	: C22H22F3NO
Mol.Wt.	: 373.4
Inv. Status	: In Stock

Cinacalcet

SZ CAT No:	: SZ-C036031
CAS No	: 226256-56-0
Mol.F.	: C22H22F3N
Mol.Wt.	: 357.4
Inv. Status	: Out of Stock
Rel. CAS No	: 364782-34-3 (HCl salt)

Cinacalcet Impurity 16

SZ CAT No:	: SZ-C036032
CAS No	: 1431699-53-4
Mol.F.	: C22H22F3N
Mol.Wt.	: 357.4
Inv. Status	: Limited Stock
Rel. CAS No	: 2469242-96-2 (HCl salt)
Rel. CAT No	: SZ-C036085 ,

Cinacalcet Regio Isomer (Napthalene 2-yl) HCl

SZ CAT No:	: SZ-C036033
CAS No	: 2200269-28-7
Mol.F.	: C22H22F3N : HCl
Mol.Wt.	: 357.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 2074615-22-6 (free base)

2-Naphthyl Cinacalcet

SZ CAT No:	: SZ-C036035
CAS No	: 1622173-74-3
Mol.F.	: C22H22F3N : HCl
Mol.Wt.	: 357.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1622203-34-2 (free base)

Cinacalcet Impurity 2(Z)

SZ CAT No:	: SZ-C036018
CAS No	: 100485-59-4
Mol.F.	: C12H11NO
Mol.Wt.	: 185.2
Inv. Status	: In Stock

Cinacalcet Impurity 20

SZ CAT No:	: SZ-C036036
CAS No	: 21172-41-8
Mol.F.	: C10H9F3O
Mol.Wt.	: 202.2
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 21

SZ CAT No:	: SZ-C036037
CAS No	: 70311-33-0
Mol.F.	: C12H13F3O2
Mol.Wt.	: 246.2
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 23

SZ CAT No:	: SZ-C036039
CAS No	: 454-89-7
Mol.F.	: C8H5F3O
Mol.Wt.	: 174.1
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 24

SZ CAT No:	: SZ-C036040
CAS No	: 376641-58-6
Mol.F.	: C10H9F3O
Mol.Wt.	: 202.2
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 25

SZ CAT No:	: SZ-C036041
CAS No	: 166947-09-7
Mol.F.	: C10H9F3O
Mol.Wt.	: 202.2
Inv. Status	: In Stock

Cinacalcet Impurity 26

SZ CAT No:	: SZ-C036042
CAS No	: 42882-31-5
Mol.F.	: C12H13N
Mol.Wt.	: 171.2
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 27

SZ CAT No:	: SZ-C036043
CAS No	: 10420-89-0
Mol.F.	: C12H13N
Mol.Wt.	: 171.2
Inv. Status	: In Stock

Cinacalcet Impurity 28

SZ CAT No:	: SZ-C036044
CAS No	: 1201-74-7
Mol.F.	: C12H13N
Mol.Wt.	: 172.2
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 29

SZ CAT No:	: SZ-C036045
CAS No	: 15297-33-3
Mol.F.	: C13H15N
Mol.Wt.	: 185.3
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 3

SZ CAT No:	: SZ-C036019
CAS No	: 1517-72-2
Mol.F.	: C12H12O
Mol.Wt.	: 172.2
Inv. Status	: In Stock

Cinacalcet Impurity 30

SZ CAT No:	: SZ-C036046
CAS No	: 1344557-18-1
Mol.F.	: C13H15N
Mol.Wt.	: 185.3
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 31

SZ CAT No:	: SZ-C036047
CAS No	: 1005450-55-4
Mol.F.	: C22H20F3NO
Mol.Wt.	: 371.4
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 32

SZ CAT No:	: SZ-C036048
CAS No	: 802918-35-0
Mol.F.	: C22H24F3N
Mol.Wt.	: 359.4
Inv. Status	: Custom Synthesis

5,6-dihydro Cinacalcet

SZ CAT No:	: SZ-C036049
CAS No	: 802918-36-1
Mol.F.	: C22H24F3N
Mol.Wt.	: 359.4
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 34

SZ CAT No:	: SZ-C036050
CAS No	: 2059891-96-0
Mol.F.	: C22H22F3N
Mol.Wt.	: 357.4
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 35

SZ CAT No:	: SZ-C036051
CAS No	: 2059891-97-1
Mol.F.	: C22H22F3N
Mol.Wt.	: 357.4
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 36

SZ CAT No:	: SZ-C036052
CAS No	: 1229225-42-6
Mol.F.	: C20H18F3N : HCl
Mol.Wt.	: 329.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1229512-52-0 (free base)

Cinacalcet Impurity 37

SZ CAT No:	: SZ-C036053
CAS No	: 938177-81-2
Mol.F.	: C21H23N : HCl
Mol.Wt.	: 289.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 253337-26-7 (free base)

Cinacalcet Impurity 38

SZ CAT No:	: SZ-C036054
CAS No	: 2609807-97-6
Mol.F.	: C22H23F2N : HCl
Mol.Wt.	: 339.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1025064-41-8 (free base)

Cinacalcet Impurity 39

SZ CAT No:	: SZ-C036055
CAS No	: NA
Mol.F.	: C22H20F3NO
Mol.Wt.	: 371.4
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 4

SZ CAT No:	: SZ-C036020
CAS No	: 7228-47-9
Mol.F.	: C12H12O
Mol.Wt.	: 172.2
Inv. Status	: In Stock

Cinacalcet Impurity 40

SZ CAT No:	: SZ-C036056
CAS No	: 113048-68-3
Mol.F.	: C12H11F3O2
Mol.Wt.	: 244.2
Inv. Status	: Custom Synthesis

Cinacalcet Nitroso Impurity 1

SZ CAT No:	: SZ-C036058
CAS No	: NA
Mol.F.	: C22H19F3N2O
Mol.Wt.	: 384.4
Inv. Status	: In Stock

Cinacalcet Impurity 44

SZ CAT No:	: SZ-C036060
CAS No	: 129254-76-8
Mol.F.	: C10H10BrF3
Mol.Wt.	: 267.1
Inv. Status	: In Stock

Cinacalcet Impurity 45

SZ CAT No:	: SZ-C036061
CAS No	: NA
Mol.F.	: C22H31N : HCl
Mol.Wt.	: 309.5 : 36.5
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 46

SZ CAT No:	: SZ-C036064
CAS No	: NA
Mol.F.	: C10H17F3O
Mol.Wt.	: 210.2
Inv. Status	: Custom Synthesis

Cinacalcet Impurity 47

SZ CAT No:	: SZ-C036065
CAS No	: 1298419-35-8
Mol.F.	: C18H16N2O4S
Mol.Wt.	: 356.4
Inv. Status	: In Stock

Cinacalcet Impurity 5 ( E )

SZ CAT No:	: SZ-C036021
CAS No	: 100485-51-6
Mol.F.	: C12H11NO
Mol.Wt.	: 185.2
Inv. Status	: In Stock

Cinacalcet Impurity 6

SZ CAT No:	: SZ-C036022
CAS No	: 941-98-0
Mol.F.	: C12H10O
Mol.Wt.	: 170.2
Inv. Status	: In Stock

Cinacalcet Impurity 7

SZ CAT No:	: SZ-C036023
CAS No	: 585-50-2
Mol.F.	: C10H9F3O2
Mol.Wt.	: 218.2
Inv. Status	: In Stock

Cinacalcet Impurity 8

SZ CAT No:	: SZ-C036024
CAS No	: 67801-07-4
Mol.F.	: C10H7F3O2
Mol.Wt.	: 216.2
Inv. Status	: In Stock

Cinacalcet Impurity 9

SZ CAT No:	: SZ-C036025
CAS No	: 41917-83-3
Mol.F.	: C10H7F3O
Mol.Wt.	: 200.2
Inv. Status	: Custom Synthesis

Cinacalcet Impurity A

SZ CAT No:	: SZ-C036007
CAS No	: 82572-04-1
Mol.F.	: C12H13N : HCl
Mol.Wt.	: 171.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 3886-70-2 (free base)

Cinacalcet Impurity B

SZ CAT No:	: SZ-C036008
CAS No	: 163831-65-0
Mol.F.	: C19H19N : HCl
Mol.Wt.	: 261.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 66469-40-7 (free base)

Cinacalcet Impurity C

SZ CAT No:	: SZ-C036009
CAS No	: 1207533-91-2
Mol.F.	: C22H20F3N : HCl
Mol.Wt.	: 355.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1201910-96-4 (free base)

Cinacalcet Impurity E

SZ CAT No:	: SZ-C036010
CAS No	: 2705511-09-5
Mol.F.	: C22H25N : HCl
Mol.Wt.	: 303.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 253337-60-9 (free base)

Cinacalcet Impurity F

SZ CAT No:	: SZ-C036011
CAS No	: NA
Mol.F.	: C22H28F3N : HCl
Mol.Wt.	: 363.5 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1271930-12-1 (free base)

Cinacalcet N-Oxide

SZ CAT No:	: SZ-C036015
CAS No	: 1229224-94-5
Mol.F.	: C22H22F3NO
Mol.Wt.	: 373.4
Inv. Status	: Custom Synthesis

Cinacalcet USP Related Compound A

SZ CAT No:	: SZ-C036002
CAS No	: 21172-43-0
Mol.F.	: C11H13F3O3S
Mol.Wt.	: 282.3
Inv. Status	: Custom Synthesis

Cinacalcet USP Related Compound B

SZ CAT No:	: SZ-C036003
CAS No	: NA
Mol.F.	: C32H31F6N : HCl
Mol.Wt.	: 543.6 : 36.5
Inv. Status	: Limited Stock
Rel. CAS No	: 1271930-15-4 (free base)

Cinacalcet USP Related Compound C

SZ CAT No:	: SZ-C036004
CAS No	: 1428118-39-1
Mol.F.	: C22H22F3N : HCl
Mol.Wt.	: 357.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1428185-71-0 (free base)

Cinacalcet USP Related Compound E

SZ CAT No:	: SZ-C036006
CAS No	: 78573-45-2
Mol.F.	: C10H11F3O
Mol.Wt.	: 204.2
Inv. Status	: In Stock

Cinacalcet USP Related Compound D

SZ CAT No:	: SZ-C036005
CAS No	: 1217809-88-5
Mol.F.	: C22H22F3N : HCl
Mol.Wt.	: 357.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 694495-47-1 (free base)

(E)-2,3,-Dehydro-cinacalcet

SZ CAT No:	: SZ-C036063
CAS No	: 955373-56-5
Mol.F.	: C22H20F3N
Mol.Wt.	: 355.4
Inv. Status	: Custom Synthesis

N-Nitroso-Cinacalcet

SZ CAT No:	: SZ-C036062
CAS No	: NA
Mol.F.	: C22H21F3N2O
Mol.Wt.	: 386.4
Inv. Status	: In Stock

Cinacalcet 7,8-Dihydro Racemate Base

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