Chemical Name: 4-[4-[[2-[[4-[4-[bis(2-chloroethyl)amino]phenyl]butanoyl]oxy]ethyl](2-chloroethyl)amino]phenyl]butanoic acid (as per EP)
Synonym: Chlorambucil Dimer Impurity
Smiles: O=C(O)CCCC1=CC=C(N(CCOC(CCCC2=CC=C(N(CCCl)CCCl)C=C2)=O)CCCl)C=C1
Inchi: InChI=1S/C16H22Cl3NO2/c17-8-11-20(12-9-18)15-6-4-14(5-7-15)2-1-3-16(21)22-13-10-19/h4-7H,1-3,8-13H2
Method development and validation for the estimation of chlorambucil in bulk and pharmaceutical dosage forms using UV-VIS spectrophotometric method
By Dey, Suddhasattya; Samal, Himansu Bhusan; Monica, P.; Reddy, Sandeep; Karthik, G.; Gujrati, Rohit; Geeta, B.
From Journal of Pharmacy Research (2011), 4(9), 3244-3246
High-performance liquid chromatography of chlorambucil analogs
By Workman, P.; Oppitz, M.; Donaldson, J.; Lee, F. Y. F.
From Journal of Chromatography, Biomedical Applications (1987), 422, 315-21