Cefadroxil Monohydrate

SZ CAT No:	SZ-C061001
CAS No	66592-87-8
Mol.F.	C16H17N3O5S : H2O
Mol.Wt.	363.4 : 18.0
Inv. Status	In Stock
Rel. CAS No	50370-12-2 (free base)
Shipping Condition	Ambient Temperature

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Chemical Name: (6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate (as per EP); (6R,7R)-7-[(R)-2-Amino-2-(p-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate (as per USP)

Synonym: p-Hydroxycephalexine Monohydrate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: OC(C(N1[C@@]2([H])[C@H](NC([C@@H](C3=CC=C(O)C=C3)N)=O)C1=O)=C(CS2)C)=O.O

Stability indicating RP - HPLC method for combination of ambroxol hydrochloride and cefadroxil monohydrate in pharmaceutical formulation
By Goswami, J. A.; Shah, N. J.
From International Journal of Pharmaceutical Sciences and Research (2017), 8(3), 1220-1228

Method development & comparative statistical evaluation of HPLC & HPTLC method for simultaneous estimation of cefadroxil monohydrate & ambroxol hydrochloride
By Dhoka, Madhura V.; Chopade, Shakuntala S.
From Indo Global Journal of Pharmaceutical Sciences (2012), 2(2), 203-212

Cefadroxil Monohydrate is chemically (6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate (as per EP); (6R,7R)-7-[(R)-2-Amino-2-(p-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate (as per USP). It is also known as p-Hydroxycephalexine Monohydrate. Cefadroxil Monohydrate is supplied with detailed characterization data compliant with regulatory guideline. Cefadroxil Monohydrate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cefadroxil.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Cefadroxil Monohydrate

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