Brexpiprazole Impurity 8

SZ CAT No:	SZ-B011009
CAS No	NA
Mol.F.	C33H31N3O2S2
Mol.Wt.	565.8
Inv. Status	Custom Synthesis

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Chemical Name: 7-(4-(4-([2,4'-Bibenzo[b]thiophen]-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C1NC2=CC(OCCCCN3CCN(C4=C(C=C(C5=CC=CC6=C5C=CS6)S7)C7=CC=C4)CC3)=CC=C2C=C1

Development and validation of stability indicating RP-HPLC method for estimation of Brexpiprazole in tablet
By Jaiswal, Chandrakant C.; Patel, Harsha U.
From World Journal of Pharmacy and Pharmaceutical Sciences (2020), 9(6), 1568-1582

Stability indicating TLC method for quantification of Brexpiprazole in bulk and its pharmaceutical dosage form and determination of content uniformity
By Thakkar, Anjali M.; Chhalotiya, Usmangani K.; Parekh, Nikunj; Desai, Jaineel V.; Shah, Dimal A.
From Journal of Chromatographic Science (2019), 57(7), 644-652

A new stability indicating RP-HPLC method for estimation of brexpiprazole
By Kumar, Vanapalli Goutham; Mondal, Sumanta
From Journal of Drug Delivery and Therapeutics (2019), 9(2Suppl.), 214-222

Brexpiprazole Impurity 8 is chemically 7-(4-(4-([2,4'-Bibenzo[b]thiophen]-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one. Brexpiprazole Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Brexpiprazole Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Brexpiprazole.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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5- Bromobenzo[b]thiophene

SZ CAT No:	: SZ-B011077
CAS No	: 4923-87-9
Mol.F.	: C8H5BrS
Mol.Wt.	: 213.1
Inv. Status	: Custom Synthesis

6-Bromobenzo[b]thiophene

SZ CAT No:	: SZ-B011053
CAS No	: 17347-32-9
Mol.F.	: C8H5BrS
Mol.Wt.	: 213.1
Inv. Status	: Custom Synthesis

7-Bromobenzo[b]thiophene

SZ CAT No:	: SZ-B011054
CAS No	: 1423-61-6
Mol.F.	: C8H5BrS
Mol.Wt.	: 213.1
Inv. Status	: Custom Synthesis

Brexpiprazole

SZ CAT No:	: SZ-B011001
CAS No	: 913611-97-9
Mol.F.	: C25H27N3O2S
Mol.Wt.	: 433.6
Inv. Status	: In Stock
Rel. CAS No	: 1420987-74-1 (HCl salt) ; 1427049-36-2 (HBr salt) ; 913612-39-2 (Sulfate salt)

Brexpiprazole Carbamate Impurity

SZ CAT No:	: SZ-B011069
CAS No	: NA
Mol.F.	: C26H27N3O4S
Mol.Wt.	: 477.6
Inv. Status	: Custom Synthesis

Brexpiprazole Cyclic Dimer

SZ CAT No:	: SZ-B011059
CAS No	: 2190474-85-0
Mol.F.	: C50H54N6O4S2
Mol.Wt.	: 867.1
Inv. Status	: Custom Synthesis

Brexpiprazole D8

SZ CAT No:	: SZ-B011D01
CAS No	: 1427049-19-1
Mol.F.	: C25H19D8N3O2S
Mol.Wt.	: 441.6
Inv. Status	: Custom Synthesis

Brexpiprazole Di-N-Oxide

SZ CAT No:	: SZ-B011028
CAS No	: 2247155-42-4
Mol.F.	: C25H27N3O4S
Mol.Wt.	: 465.6
Inv. Status	: In Stock

Brexpiprazole Hydrobromide

SZ CAT No:	: SZ-B011023
CAS No	: 1427049-36-2
Mol.F.	: C25H27N3O2S : HBr
Mol.Wt.	: 433.6 : 80.9
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1420987-74-1 (HCl salt) ; 913611-97-9 (free base) ; 913612-39-2 (Sulfate salt)

Brexpiprazole Hydrochloride

SZ CAT No:	: SZ-B011003
CAS No	: 1420987-74-1
Mol.F.	: C25H27N3O2S : HCl
Mol.Wt.	: 433.6 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 913611-97-9 (free base) ; 1427049-36-2 (HBr salt) ; 913612-39-2 (Sulfate salt)

Brexpiprazole Impurity 1

SZ CAT No:	: SZ-B011002
CAS No	: 1420987-86-5
Mol.F.	: C20H18N2S2
Mol.Wt.	: 350.5
Inv. Status	: In Stock

Brexpiprazole Impurity 10

SZ CAT No:	: SZ-B011011
CAS No	: 15116-41-3
Mol.F.	: C16H15NO2
Mol.Wt.	: 253.3
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 11

SZ CAT No:	: SZ-B011012
CAS No	: 1886188-97-1
Mol.F.	: C13H15NO3
Mol.Wt.	: 233.3
Inv. Status	: In Stock

Brexpiprazole Impurity 12

SZ CAT No:	: SZ-B011013
CAS No	: 2116542-19-7
Mol.F.	: C22H20N2O4
Mol.Wt.	: 376.4
Inv. Status	: In Stock

Brexpiprazole Impurity 13

SZ CAT No:	: SZ-B011014
CAS No	: NA
Mol.F.	: C25H27N3O2S
Mol.Wt.	: 433.6
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 14

SZ CAT No:	: SZ-B011015
CAS No	: 2518081-42-8
Mol.F.	: C38H40N4O4S
Mol.Wt.	: 648.8
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 15

SZ CAT No:	: SZ-B011016
CAS No	: 913612-07-4
Mol.F.	: C25H29N3O2S
Mol.Wt.	: 435.6
Inv. Status	: In Stock
Rel. CAS No	: 2389989-56-2 (HCl salt)

Brexpiprazole Impurity 16

SZ CAT No:	: SZ-B011017
CAS No	: NA
Mol.F.	: C33H33N3O2S2
Mol.Wt.	: 567.8
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 17

SZ CAT No:	: SZ-B011018
CAS No	: 2250242-22-7
Mol.F.	: C28H34N4S2
Mol.Wt.	: 490.7
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 18

SZ CAT No:	: SZ-B011019
CAS No	: 2059954-32-2
Mol.F.	: C17H21Cl2NO2
Mol.Wt.	: 342.3
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 19

SZ CAT No:	: SZ-B011020
CAS No	: 616227-75-9
Mol.F.	: C15H13NO2
Mol.Wt.	: 239.3
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 20

SZ CAT No:	: SZ-B011022
CAS No	: 1420987-85-4
Mol.F.	: C20H20N2S2
Mol.Wt.	: 352.5
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 22

SZ CAT No:	: SZ-B011024
CAS No	: 913614-18-3
Mol.F.	: C12H14N2S : HCl
Mol.Wt.	: 218.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 846038-18-4 (free base) ; 2220149-86-8 (sulfate salt)

Brexpiprazole Impurity 23

SZ CAT No:	: SZ-B011025
CAS No	: 1849603-58-2
Mol.F.	: C17H23N3O2
Mol.Wt.	: 301.4
Inv. Status	: In Stock
Rel. CAS No	: 1890994-10-1 (HCl salt)

Brexpiprazole Impurity 24

SZ CAT No:	: SZ-B011026
CAS No	: 2220149-92-6
Mol.F.	: C30H36N4O4
Mol.Wt.	: 516.6
Inv. Status	: In Stock

Brexpiprazole Impurity 25

SZ CAT No:	: SZ-B011027
CAS No	: 5118-13-8
Mol.F.	: C8H5BrS
Mol.Wt.	: 213.1
Inv. Status	: In Stock

Brexpiprazole Impurity 26

SZ CAT No:	: SZ-B011029
CAS No	: 913613-82-8
Mol.F.	: C13H14ClNO2
Mol.Wt.	: 251.7
Inv. Status	: In Stock

Brexpiprazole Impurity 27

SZ CAT No:	: SZ-B011030
CAS No	: 95-15-8
Mol.F.	: C8H6S
Mol.Wt.	: 134.2
Inv. Status	: In Stock

Brexpiprazole Impurity 28

SZ CAT No:	: SZ-B011031
CAS No	: 203395-59-9
Mol.F.	: C13H14BrNO2
Mol.Wt.	: 296.2
Inv. Status	: In Stock

Brexpiprazole Impurity 29

SZ CAT No:	: SZ-B011032
CAS No	: 1191901-09-3
Mol.F.	: C13H14INO2
Mol.Wt.	: 343.2
Inv. Status	: In Stock

Brexpiprazole Impurity 30

SZ CAT No:	: SZ-B011033
CAS No	: 2094559-58-5
Mol.F.	: C38H40N4O4S
Mol.Wt.	: 648.8
Inv. Status	: In Stock

Brexpiprazole Impurity 31

SZ CAT No:	: SZ-B011034
CAS No	: 2138169-93-2
Mol.F.	: C41H47N5O2S2
Mol.Wt.	: 706.0
Inv. Status	: In Stock

Brexpiprazole Impurity 32

SZ CAT No:	: SZ-B011035
CAS No	: 2143944-64-1
Mol.F.	: C16H21N2S
Mol.Wt.	: 273.4
Inv. Status	: In Stock

Brexpiprazole Impurity 33

SZ CAT No:	: SZ-B011036
CAS No	: NA
Mol.F.	: C16H20N2S
Mol.Wt.	: 272.4
Inv. Status	: In Stock

Brexpiprazole Impurity 34

SZ CAT No:	: SZ-B011037
CAS No	: 2116542-21-1
Mol.F.	: C38H40N4O4S
Mol.Wt.	: 648.8
Inv. Status	: In Stock

Brexpiprazole Impurity 35

SZ CAT No:	: SZ-B011038
CAS No	: NA
Mol.F.	: C25H27N3O4S
Mol.Wt.	: 465.6
Inv. Status	: Out of Stock

Brexpiprazole Impurity 36

SZ CAT No:	: SZ-B011039
CAS No	: NA
Mol.F.	: C13H14BrNO2
Mol.Wt.	: 296.2
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 37

SZ CAT No:	: SZ-B011040
CAS No	: NA
Mol.F.	: C13H14ClNO2
Mol.Wt.	: 251.7
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 38

SZ CAT No:	: SZ-B011041
CAS No	: NA
Mol.F.	: C13H14BrNO2
Mol.Wt.	: 296.2
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 39

SZ CAT No:	: SZ-B011042
CAS No	: 2059942-13-9
Mol.F.	: C26H27ClN2O4
Mol.Wt.	: 467.0
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2059942-14-0 (HCl salt)

Brexpiprazole Impurity 4

SZ CAT No:	: SZ-B011005
CAS No	: 2116542-20-0
Mol.F.	: C25H27N3O2S
Mol.Wt.	: 433.6
Inv. Status	: Out of Stock

Brexpiprazole Impurity 40

SZ CAT No:	: SZ-B011043
CAS No	: 2060029-80-1
Mol.F.	: C26H27ClN2O4
Mol.Wt.	: 467.0
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 41

SZ CAT No:	: SZ-B011044
CAS No	: NA
Mol.F.	: C26H27BrN2O4
Mol.Wt.	: 511.4
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 42

SZ CAT No:	: SZ-B011045
CAS No	: 2060027-95-2
Mol.F.	: C17H21Cl2NO2
Mol.Wt.	: 342.3
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 43

SZ CAT No:	: SZ-B011046
CAS No	: NA
Mol.F.	: C26H27BrN2O4
Mol.Wt.	: 511.4
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 44

SZ CAT No:	: SZ-B011047
CAS No	: NA
Mol.F.	: C26H27BrN2O4
Mol.Wt.	: 511.4
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 45

SZ CAT No:	: SZ-B011048
CAS No	: NA
Mol.F.	: C17H21Br2NO2
Mol.Wt.	: 431.2
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 46

SZ CAT No:	: SZ-B011049
CAS No	: NA
Mol.F.	: C25H27N3O2S
Mol.Wt.	: 433.6
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 48 (Iodide)

SZ CAT No:	: SZ-B011051
CAS No	: 2454317-19-0
Mol.F.	: C38H41N4O4S : I
Mol.Wt.	: 649.8 : 126.9
Inv. Status	: In Stock
Rel. CAS No	: 2454317-16-7 (free base) ; 2454317-17-8 (chloride salt)

Brexpiprazole Impurity 49

SZ CAT No:	: SZ-B011052
CAS No	: NA
Mol.F.	: C13H14ClNO2
Mol.Wt.	: 251.7
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 5

SZ CAT No:	: SZ-B011064
CAS No	: 105685-34-5
Mol.F.	: C12H14N2O
Mol.Wt.	: 202.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 105684-85-3 (HCl salt)

Brexpiprazole Impurity 50

SZ CAT No:	: SZ-B011055
CAS No	: NA
Mol.F.	: C17H23Cl2NO2
Mol.Wt.	: 344.3
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 51

SZ CAT No:	: SZ-B011056
CAS No	: NA
Mol.F.	: C41H49N5O2S2
Mol.Wt.	: 708.0
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 52

SZ CAT No:	: SZ-B011057
CAS No	: 2137823-20-0
Mol.F.	: C41H47N5O2S2
Mol.Wt.	: 706.0
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 53

SZ CAT No:	: SZ-B011058
CAS No	: NA
Mol.F.	: C38H42N4O4S
Mol.Wt.	: 650.8
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 54

SZ CAT No:	: SZ-B011061
CAS No	: 17913-18-7
Mol.F.	: C5H11ClO
Mol.Wt.	: 122.6
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 55

SZ CAT No:	: SZ-B011062
CAS No	: 4457-67-4
Mol.F.	: C5H11BrO
Mol.Wt.	: 167.0
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 56

SZ CAT No:	: SZ-B011063
CAS No	: 13179-96-9
Mol.F.	: C6H14O2
Mol.Wt.	: 118.2
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 57

SZ CAT No:	: SZ-B011071
CAS No	: 57260-71-6
Mol.F.	: C9H18N2O2
Mol.Wt.	: 186.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 76535-74-5 (HCl salt)

Brexpiprazole Impurity 58

SZ CAT No:	: SZ-B011072
CAS No	: 76535-75-6
Mol.F.	: C14H26N2O4
Mol.Wt.	: 286.4
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 59

SZ CAT No:	: SZ-B011073
CAS No	: 310466-38-7
Mol.F.	: C8H5FS
Mol.Wt.	: 152.2
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 6

SZ CAT No:	: SZ-B011007
CAS No	: NA
Mol.F.	: C25H27N3O3
Mol.Wt.	: 417.5
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 60

SZ CAT No:	: SZ-B011074
CAS No	: 2081876-02-8
Mol.F.	: C22H31N3O4
Mol.Wt.	: 401.5
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 61

SZ CAT No:	: SZ-B011075
CAS No	: 584-45-2
Mol.F.	: C10H8O4
Mol.Wt.	: 192.2
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 62

SZ CAT No:	: SZ-B011076
CAS No	: 1224935-95-8
Mol.F.	: C15H28N2O2
Mol.Wt.	: 268.4
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 7

SZ CAT No:	: SZ-B011008
CAS No	: 2126178-13-8
Mol.F.	: C20H18N2S2
Mol.Wt.	: 350.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2126178-14-9 (HCl salt)

Brexpiprazole Impurity 7 Hydrochloride

SZ CAT No:	: SZ-B011065
CAS No	: 2126178-14-9
Mol.F.	: C20H18N2S2 : 2(HCl)
Mol.Wt.	: 350.5 : 2(36.5)
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2126178-13-8 (free base)

Brexpiprazole Impurity 8

SZ CAT No:	: SZ-B011009
CAS No	: NA
Mol.F.	: C33H31N3O2S2
Mol.Wt.	: 565.8
Inv. Status	: Custom Synthesis

Brexpiprazole Impurity 9

SZ CAT No:	: SZ-B011010
CAS No	: 31570-97-5
Mol.F.	: C9H7NO2
Mol.Wt.	: 161.2
Inv. Status	: Custom Synthesis

Brexpiprazole N-Oxide

SZ CAT No:	: SZ-B011004
CAS No	: 1191900-58-9
Mol.F.	: C25H27N3O3S
Mol.Wt.	: 449.6
Inv. Status	: Out of Stock

Brexpiprazole Sulfate

SZ CAT No:	: SZ-B011060
CAS No	: 913612-39-2
Mol.F.	: C25H27N3O2S : H2SO4
Mol.Wt.	: 433.6 : 98.1
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1420987-74-1 (HCl salt) ; 1427049-36-2 (HBr salt) ; 913611-97-9 (free base)

Brexpiprazole Sulfoxide

SZ CAT No:	: SZ-B011021
CAS No	: 1191900-51-2
Mol.F.	: C25H27N3O3S
Mol.Wt.	: 449.6
Inv. Status	: Out of Stock, Custom Synthesis

Brexpiprazole-Piperazin D8

SZ CAT No:	: SZ-B011D02
CAS No	: 1427049-21-5
Mol.F.	: C25H19D8N3O2S
Mol.Wt.	: 441.6
Inv. Status	: Custom Synthesis

N-Nitroso Brexpiprazole Impurity

SZ CAT No:	: SZ-B011070
CAS No	: 2761668-93-1
Mol.F.	: C20H19N3OS2
Mol.Wt.	: 381.5
Inv. Status	: Custom Synthesis

N-Nitroso Brexpiprazole Impurity 1

SZ CAT No:	: SZ-B011078
CAS No	: 877177-42-9
Mol.F.	: C9H17N3O3
Mol.Wt.	: 215.3
Inv. Status	: In Stock

Brexpiprazole Impurity 8

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