Betamethasone Acetate EP Impurity C

SZ CAT No:	SZ-B025015
CAS No	330157-05-6
Mol.F.	C26H33FO7
Mol.Wt.	476.5
Inv. Status	In Stock

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: 9-Fluoro-17-hydroxy-16β-methyl-3,20-dioxopregna-1,4-diene-11β,21-diyl diacetate (as per EP) ; 9-Fluoro-11Beta,17,21-trihydroxy-16Beta-methylpregna-1,4-diene-3,20-dione 11,21-diacetate (as per USP)

Synonym: Betamethasone Acetate USP Related Compound C ; Betamethasone 11,21-Diacetate (EP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: C[C@@]12[C@](C(COC(C)=O)=O)(O)[C@@H](C)C[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](OC(C)=O)C2)=O

Application of LC–MSn in conjunction with mechanism-based stress studies in the elucidation of drug impurity structure: Rapid identification of a process impurity in betamethasone 17-valerate drug substance
Min Li, Mingxiang Lin, Abu Rustum
Journal of Pharmaceutical and Biomedical Analysis 48 (2008) 1451–1456

Development and Validation of Stability-indicating HPLC Method for Betamethoasone Dipropionate and Related Substances in Topical Formulation
A. s. vairale*, p. sivaswaroop1 and s. bandana
Indian Journal of Pharmaceutical Sciences 74(2):107-15

Betamethasone Acetate EP Impurity C is chemically 9-Fluoro-17-hydroxy-16β-methyl-3,20-dioxopregna-1,4-diene-11β,21-diyl diacetate (as per EP) ; 9-Fluoro-11Beta,17,21-trihydroxy-16Beta-methylpregna-1,4-diene-3,20-dione 11,21-diacetate (as per USP). It is also known as Betamethasone Acetate USP Related Compound C ; Betamethasone 11,21-Diacetate (EP) . Betamethasone Acetate EP Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Betamethasone Acetate EP Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Betamethasone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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16(17)a-Homobetamethasone Sodium Phosphate

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Lumibetamethasone Dipropionate

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Δ-4,6-Betamethasone

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Δ-9,11-Betamethasone 21-Acetate

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Betamethasone Acetate EP Impurity C

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