Bendamustine Hydrochloride

SZ CAT No:	SZ-B010000
CAS No	3543-75-7
Mol.F.	C16H202N3O2 : HCl
Mol.Wt.	358.3 : 36.5
Inv. Status	In Stock
Rel. CAS No	16506-27-7 (free base)
Shipping Condition	Ambient Temperature

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: 4-{5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-yl}butanoic acid monohydrochloride (as per USP)

Synonym: Cytostasan ; Ribomustin ; Treanda

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CN1C(C=C2)=C(N=C1CCCC(O)=O)C=C2N(CCCl)CCCl.Cl

Polymorphic forms of bendamustine hydrochloride: crystal structure, thermal properties and stability at ambient conditions
By Gaztanaga, Pablo; Baggio, Ricardo; Vega, Daniel Roberto
From Acta Crystallographica, Section B: Structural Science, Crystal Engineering and Materials (2019), 75(6), 933-941

Development and validation of a stability-indicating rp-hplc method for the determination of bendamustine in raw material and finished product
By Dhananjaya, G.; Naveen, M.; Pathi, P. Janaki; Raghuram, J.; Raju, N. Appala
From World Journal of Pharmaceutical Research (2018), 7(18), 1172-1187

Novel validated RP-HPLC method for bendamustine hydrochloride based on ion-pair chromatography: application in determining infusion stability and pharmacokinetics
By Singh, Yuvraj; Chandrashekar, Anumandla; Pawar, Vivek K.; Saravanakumar, Veeramuthu; Meher, Jayagopal; Raval, Kavit; Singh, Pankaj; Kumar, R. Dinesh; Chourasia, Manish K.
From Journal of Chromatographic Science (2017), 55(1), 30-39

Stability- indicating novel HPLC method for estimation of Bendamustine in pharmaceutical forms
By Reddy, Gade Srinivas; Reddy, S. L. N. Prasad; Reddy, L. Shiva kumar
From American Journal of PharmTech Research (2016), 6(2), 343-357

Bendamustine Hydrochloride is chemically 4-{5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-yl}butanoic acid monohydrochloride (as per USP) . It is also known as Cytostasan ; Ribomustin ; Treanda . Bendamustine Hydrochloride is supplied with detailed characterization data compliant with regulatory guideline. Bendamustine Hydrochloride can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bendamustine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Bendamustine Hydrochloride

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SZ CAT No:	: SZ-B010007
CAS No	: 16506-27-7
Mol.F.	: C16H21Cl2N3O2
Mol.Wt.	: 358.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 3543-75-7 (HCl salt) ; 1374784-02-7 (hydrochloride hydrate)

SZ CAT No:	: SZ-B010047
CAS No	: NA
Mol.F.	: C15H21N3O2 : HCl
Mol.Wt.	: 275.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1313020-26-6 (free base)

SZ CAT No:	: SZ-B010D02
CAS No	: 1185068-23-8
Mol.F.	: C16H13D8Cl2N3O2 : HCl
Mol.Wt.	: 366.3 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1134803-33-0 (free base)

SZ CAT No:	: SZ-B010001
CAS No	: 2517968-40-8
Mol.F.	: C16H22ClN3O2
Mol.Wt.	: 323.8
Inv. Status	: In Stock

SZ CAT No:	: SZ-B010003
CAS No	: 914626-62-3
Mol.F.	: C12H15N3O2
Mol.Wt.	: 233.3
Inv. Status	: In Stock
Rel. CAS No	: 1179363-38-2 (HCl salt)

SZ CAT No:	: SZ-B010019
CAS No	: NA
Mol.F.	: C35H45Cl3N6O4 : HCl
Mol.Wt.	: 720.2 : 36.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010021
CAS No	: 2173004-95-8
Mol.F.	: C16H21N3O3 : HCl
Mol.Wt.	: 303.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1228552-02-0 (Free base)

SZ CAT No:	: SZ-B010000
CAS No	: 3543-75-7
Mol.F.	: C16H202N3O2 : HCl
Mol.Wt.	: 358.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 16506-27-7 (free base)

SZ CAT No:	: SZ-B010015
CAS No	: NA
Mol.F.	: C32H43ClN6O6 : HCl
Mol.Wt.	: 643.2 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1219709-87-1 (free base)

SZ CAT No:	: SZ-B010022
CAS No	: NA
Mol.F.	: C16H23N3O3 : HCl
Mol.Wt.	: 305.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1366085-72-4 (free base)

SZ CAT No:	: SZ-B010031
CAS No	: NA
Mol.F.	: C12H15N3O5 : HCl
Mol.Wt.	: 281.3 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 91644-13-2 (free base)

SZ CAT No:	: SZ-B010032
CAS No	: NA
Mol.F.	: C19H22N6O6 : HCl
Mol.Wt.	: 430.4 : 36.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010033
CAS No	: NA
Mol.F.	: C19H20N6O5 : HCl
Mol.Wt.	: 412.4 : 36.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010034
CAS No	: 914626-65-6
Mol.F.	: C19H18N6O4
Mol.Wt.	: 394.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-B010035
CAS No	: NA
Mol.F.	: C19H22N6 : HCl
Mol.Wt.	: 334.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 847588-86-7 (free base)

SZ CAT No:	: SZ-B010036
CAS No	: 1469343-10-9
Mol.F.	: C15H21N2O2
Mol.Wt.	: 261.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010037
CAS No	: NA
Mol.F.	: C19H27Cl2N3O4
Mol.Wt.	: 432.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-B010038
CAS No	: NA
Mol.F.	: C18H24ClN3O4
Mol.Wt.	: 381.9
Inv. Status	: Out of Stock

SZ CAT No:	: SZ-B010039
CAS No	: NA
Mol.F.	: C33H46N6O6 : HCl
Mol.Wt.	: 622.8 : 36.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010040
CAS No	: 3543-73-5
Mol.F.	: C14H19N3O2
Mol.Wt.	: 261.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-B010023
CAS No	: NA
Mol.F.	: C16H21Cl2N3O3 : HCl
Mol.Wt.	: 374.3 : 36.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010044
CAS No	: 2784-96-5
Mol.F.	: C7H9N3O2
Mol.Wt.	: 167.2
Inv. Status	: In Stock
Rel. CAS No	: 879649-75-9 (HCl salt)

SZ CAT No:	: SZ-B010050
CAS No	: 7441-32-9
Mol.F.	: C30H24O12
Mol.Wt.	: 576.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010051
CAS No	: 88-26-6
Mol.F.	: C15H24O2
Mol.Wt.	: 236.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010052
CAS No	: NA
Mol.F.	: C16H19N3O2S2 : HCl
Mol.Wt.	: 349.5 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-B010069
CAS No	: 119548-63-9
Mol.F.	: C14H14N6O5
Mol.Wt.	: 346.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010070
CAS No	: NA
Mol.F.	: C15H18N6O4
Mol.Wt.	: 346.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010071
CAS No	: NA
Mol.F.	: C14H14N6O4
Mol.Wt.	: 330.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010072
CAS No	: NA
Mol.F.	: C15H16N6O2
Mol.Wt.	: 312.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B010024
CAS No	: 60651-29-8
Mol.F.	: C7H11N3
Mol.Wt.	: 137.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1305319-65-6 (HCl salt)