Atorvastatin Amlodipine Dimer

SZ CAT No:	SZ-A005033
CAS No	425408-16-8
Mol.F.	C53H58ClFN4O9
Mol.Wt.	949.5
Inv. Status	In Stock

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Chemical Name: 3-Ethyl 5-methyl 4-(2-chlorophenyl)-2-((2-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

Synonym: Atorvastatin Amlodipine Adduct

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: FC(C=C1)=CC=C1C2=C(C3=CC=CC=C3)C(C(NC4=CC=CC=C4)=O)=C(C(C)C)N2CC[C@@H](O)C[C@@H](O)CC(NCCOCC(NC(C)=C(C(OC)=O)C5C6=CC=CC=C6Cl)=C5C(OCC)=O)=O

Identification and characterization of potential impurities of amlodipine maleate
P. Sudhakar a, M. Nirmala a, J. Moses Babu a,∗, K. Vyas a, Ganta Madhusudan Reddy b, B. Vijaya Bhaskar b, P. Pratap Reddy b, K. Mukkanti c
J. Braz. Chem. Soc., Vol. 19, No. 1, 35-41, 2008.

Determination of the Absolute Configuration of the Active Amlodipine Enantiomer as (-)-S: A Correction
Siegfried Goldmann,* Jiirgen Stoltefuss, and Liborius Born
J. Med. Chem. 1992,35,3341-3344

Development of a Stability-Indicating HPLC Method for Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Bulk and Pharmaceutical Dosage Form
Hafez HM*, Elshanawany AA, Abdelaziz LM and Mohram MS
Hafez et al., Pharm Anal Acta 2014, 5:9

Atorvastatin Amlodipine Dimer is chemically 3-Ethyl 5-methyl 4-(2-chlorophenyl)-2-((2-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate. It is also known as Atorvastatin Amlodipine Adduct. Atorvastatin Amlodipine Dimer is supplied with detailed characterization data compliant with regulatory guideline. Atorvastatin Amlodipine Dimer can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Amlodipine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Amlodipine EP Impurity B

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Amlodipine EP Impurity C

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Amlodipine EP Impurity D (Fumarate salt)

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Amlodipine EP Impurity E

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Amlodipine EP Impurity F

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Amlodipine EP Impurity G

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Mol.Wt.	: 335.8
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Amlodipine EP Impurity H

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Amlodipine Impurity 1

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Amlodipine Impurity 13

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Amlodipine Impurity 27

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Amlodipine Impurity 31

SZ CAT No:	: SZ-A005071
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Hydroxyethyl Phthalyl Amlodipine

SZ CAT No:	: SZ-A005072
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Amlodipine Impurity 35

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Amlodipine Impurity 8

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Amlodipine Impurity 9

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N-Nitroso Amlodipine EP Impurity A

SZ CAT No:	: SZ-A005058
CAS No	: NA
Mol.F.	: C28H26ClN3O8
Mol.Wt.	: 568.0
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N-Nitroso Amlodipine Impurity-1

SZ CAT No:	: SZ-A005065
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Mol.F.	: C20H21ClN2O6
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Mol.Wt.	: 412.9
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Levamlodipine Besylate

SZ CAT No:	: SZ-A005014
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SZ CAT No:	: SZ-A005D03
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Mol.F.	: C20H21D4ClN2O5
Mol.Wt.	: 412.9
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Atorvastatin Amlodipine Dimer

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