Amlodipine EP Impurity E

SZ CAT No:	SZ-A005006
CAS No	140171-65-9
Mol.F.	C21H27ClN2O5
Mol.Wt.	422.9
Inv. Status	In Stock
Rel. CAS No	400024-12-6 (maleate Salt)

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Chemical Name: diethyl (4RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate (as per EP)

Synonym: Amlodipine Diethyl Ester; Amlodipine Ethyl Analog (USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C1=C(COCCN)NC(C)=C(C(OCC)=O)C1C2=CC=CC=C2Cl)OCC

Identification and characterization of potential impurities of amlodipine maleate
P. Sudhakar a, M. Nirmala a, J. Moses Babu a,∗, K. Vyas a, Ganta Madhusudan Reddy b, B. Vijaya Bhaskar b, P. Pratap Reddy b, K. Mukkanti c
J. Braz. Chem. Soc., Vol. 19, No. 1, 35-41, 2008.

Determination of the Absolute Configuration of the Active Amlodipine Enantiomer as (-)-S: A Correction
Siegfried Goldmann,* Jiirgen Stoltefuss, and Liborius Born
J. Med. Chem. 1992,35,3341-3344

Development of a Stability-Indicating HPLC Method for Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Bulk and Pharmaceutical Dosage Form
Hafez HM*, Elshanawany AA, Abdelaziz LM and Mohram MS
Hafez et al., Pharm Anal Acta 2014, 5:9

Amlodipine EP Impurity E is chemically diethyl (4RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate (as per EP). It is also known as Amlodipine Diethyl Ester; Amlodipine Ethyl Analog (USP). Amlodipine EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Amlodipine EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Amlodipine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Amlodipine Besylate

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CAS No	: 111470-99-6
Mol.F.	: C20H25ClN2O5 : C6H6O3S
Mol.Wt.	: 408.9 : 158.2
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Amlodipine EP Impurity A

SZ CAT No:	: SZ-A005002
CAS No	: 88150-62-3
Mol.F.	: C28H27ClN2O7
Mol.Wt.	: 539.0
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Amlodipine EP Impurity B

SZ CAT No:	: SZ-A005003
CAS No	: 721958-72-1
Mol.F.	: C29H32ClN3O7
Mol.Wt.	: 570.1
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Amlodipine EP Impurity C

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Amlodipine EP Impurity D (Besylate salt)

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CAS No	: 2733700-89-3
Mol.F.	: C20H23ClN2O5 : C6H6O3S
Mol.Wt.	: 406.9 : 158.2
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Amlodipine EP Impurity D (Fumarate salt)

SZ CAT No:	: SZ-A005053
CAS No	: 2138811-33-1
Mol.F.	: C20H23ClN2O5 : C4H4O4
Mol.Wt.	: 406.9 : 116.1
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Amlodipine EP Impurity E

SZ CAT No:	: SZ-A005006
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Mol.F.	: C21H27ClN2O5
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Amlodipine EP Impurity F

SZ CAT No:	: SZ-A005007
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Mol.F.	: C19H23ClN2O5
Mol.Wt.	: 394.9
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Amlodipine EP Impurity G

SZ CAT No:	: SZ-A005008
CAS No	: 43067-01-2
Mol.F.	: C17H18ClNO4
Mol.Wt.	: 335.8
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Amlodipine EP Impurity H

SZ CAT No:	: SZ-A005009
CAS No	: 318465-73-5
Mol.F.	: C28H29ClN2O8
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Ethyl benzenesulfonate

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Amlodipine Glucose + Galactose adduct

SZ CAT No:	: SZ-A005056
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Mol.F.	: C26H35ClN2O10
Mol.Wt.	: 571.0
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Amlodipine Impurity 1

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Amlodipine Impurity 10

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Amlodipine Impurity 11

SZ CAT No:	: SZ-A005030
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Mol.Wt.	: 240.3
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Amlodipine Impurity 12

SZ CAT No:	: SZ-A005034
CAS No	: NA
Mol.F.	: C23H22ClNO7
Mol.Wt.	: 459.9
Inv. Status	: Custom Synthesis

Amlodipine Impurity 13

SZ CAT No:	: SZ-A005035
CAS No	: NA
Mol.F.	: C29H32ClN3O7
Mol.Wt.	: 570.0
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Amlodipine Impurity 16

SZ CAT No:	: SZ-A005038
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Mol.F.	: C20H23ClN2O7
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Amlodipine Impurity 17

SZ CAT No:	: SZ-A005039
CAS No	: NA
Mol.F.	: C20H24ClNO6
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Amlodipine Impurity 19

SZ CAT No:	: SZ-A005041
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Mol.F.	: C26H29ClN2O7S
Mol.Wt.	: 549.1
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Amlodipine Impurity 2

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Amlodipine Impurity 23

SZ CAT No:	: SZ-A005049
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Amlodipine Impurity 24

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Amlodipine Impurity 26

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Amlodipine Impurity 27

SZ CAT No:	: SZ-A005064
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Mol.Wt.	: 393.9
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Amlodipine Impurity 28

SZ CAT No:	: SZ-A005067
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Amlodipine Impurity 3

SZ CAT No:	: SZ-A005028
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Amlodipine Impurity 30

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Mol.Wt.	: 947.9
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Amlodipine Impurity 31

SZ CAT No:	: SZ-A005071
CAS No	: 721958-75-4
Mol.F.	: C20H20ClNO5
Mol.Wt.	: 389.8
Inv. Status	: Custom Synthesis

Hydroxyethyl Phthalyl Amlodipine

SZ CAT No:	: SZ-A005072
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Mol.F.	: C30H34ClN3O8
Mol.Wt.	: 600.1
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Amlodipine Impurity 33

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Mol.Wt.	: 525.0
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Amlodipine Impurity 34

SZ CAT No:	: SZ-A005078
CAS No	: NA
Mol.F.	: C28H28ClN3O7
Mol.Wt.	: 554.0
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Amlodipine Impurity 35

SZ CAT No:	: SZ-A005079
CAS No	: NA
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Amlodipine Impurity 36

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Amlodipine Impurity 37

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Amlodipine Impurity 4

SZ CAT No:	: SZ-A005016
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Mol.Wt.	: 480.0
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Amlodipine Impurity 6

SZ CAT No:	: SZ-A005024
CAS No	: 3891-07-4
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Amlodipine Impurity 7

SZ CAT No:	: SZ-A005025
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Mol.F.	: C19H23ClN2O5
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Amlodipine Impurity 8

SZ CAT No:	: SZ-A005026
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Mol.F.	: C19H18Cl2N2O4
Mol.Wt.	: 409.3
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Amlodipine Impurity 9

SZ CAT No:	: SZ-A005027
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Amlodipine Lactone Impurity

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Amlodipine Metabolite 5

SZ CAT No:	: SZ-A005017
CAS No	: 114018-75-6
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Amlodipine Methyl Ester

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Amlodipine N-Glucose

SZ CAT No:	: SZ-A005031
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Mol.Wt.	: 571.0
Inv. Status	: In Stock

N-Nitroso Amlodipine

SZ CAT No:	: SZ-A005057
CAS No	: NA
Mol.F.	: C20H24ClN3O6
Mol.Wt.	: 437.9
Inv. Status	: Inquire

Amlodipine Nitroso Impurity 1

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Amlodipine Nitroso N-Lactoside

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Amlodipine Related Compound K

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SZ CAT No:	: SZ-A005059
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Mol.F.	: C29H31ClN4O8
Mol.Wt.	: 599.0
Inv. Status	: Inquire

N-Nitroso Amlodipine EP Impurity A

SZ CAT No:	: SZ-A005058
CAS No	: NA
Mol.F.	: C28H26ClN3O8
Mol.Wt.	: 568.0
Inv. Status	: Inquire

N-Nitroso Amlodipine Impurity-1

SZ CAT No:	: SZ-A005065
CAS No	: NA
Mol.F.	: C20H21ClN2O6
Mol.Wt.	: 420.8
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R-Amlodipine D4

SZ CAT No:	: SZ-A005D01
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Mol.F.	: C20H21D4ClN2O5
Mol.Wt.	: 412.9
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Levamlodipine Besylate

SZ CAT No:	: SZ-A005014
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S-Amlodipine D4

SZ CAT No:	: SZ-A005D03
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Mol.F.	: C20H21D4ClN2O5
Mol.Wt.	: 412.9
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Amlodipine EP Impurity E

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