Atenolol EP Impurity G

SZ CAT No:	SZ-A035008
CAS No	56392-14-4
Mol.F.	C14H21NO4
Mol.Wt.	267.3
Inv. Status	In Stock
Rel. CAS No	207287-28-3 (HCl salt) ; 162936-16-5 (potassium salt)

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Chemical Name: [4-[(2RS)-2-Hydroxy-3-[(propan-2-yl)amino]propoxy]phenyl]acetic acid (as per EP) ; 2-{4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl}acetic acid (as per USP)

Synonym: Atenolol USP Related Compound G

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CC(NCC(O)COC1=CC=C(CC(O)=O)C=C1)C

The assay and resolution of the beta-blocker atenolol from its related impurities in a tablet pharmaceutical dosage form
Zen pawlak* and Brian j. clark
Journal of Pharmaceutical & Biomedical Analysis Vol. 10, No. 5, pp. 329-334,1992

Removal of Atenolol and Isoproturon in Aqueous Solutions by Adsorption in a Fixed-Bed Column
JoséLuis Sotelo, Gabriel Ovejero, Araceli Rodríguez, Silvia Á lvarez, and Juan García
Ind. Eng. Chem. Res. 2012, 51, 5045−5055

A simple, selective, and sensitive gas chromatography-mass spectrometry method for the analysis of five process-related impurities in atenolol bulk drug and capsule formulations
Ambavaram Vijaya Bhaskar Reddy Zulkifli Yusop Jafariah Jaafar Azmi Bin Aris Zaiton Abdul Majid
JSS Volume 40, Issue 15 Pages: 3016-3182 August 2017

A Sensitive and Selective GC–MS Method for Analysis of Process-Related Genotoxic Impurities in Atenolol
Yogeshwar Reddy Mamilla1,3,&, Kista Reddy Chetyala3 , Ramesh Venna2 , Raju Gajjela2 , Kishore Katragadda1 , Saravanan Govindasamy1 , Suryanarayana Mulukutla1 , Debashish Datta
Chromatographia 2010, 71, 733–736

Development and validation of liquid chromatographic method for atenolol and its related substance
Nandini R. Pai* and Swapnali Suhas Patil
Der Pharmacia Sinica, 2013, 4(2):76-84

Atenolol EP Impurity G is chemically [4-[(2RS)-2-Hydroxy-3-[(propan-2-yl)amino]propoxy]phenyl]acetic acid (as per EP) ; 2-{4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl}acetic acid (as per USP). It is also known as Atenolol USP Related Compound G. Atenolol EP Impurity G is supplied with detailed characterization data compliant with regulatory guideline. Atenolol EP Impurity G can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Atenolol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Atenolol EP Impurity G

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