Adefovir Dipivoxil

SZ CAT No:	SZ-A075001
CAS No	142340-99-6
Mol.F.	C20H32N5O8P
Mol.Wt.	501.5
Inv. Status	Custom Synthesis
Rel. CAS No	220350-60-7 (HBr salt) ; 220350-52-7 (Sulfate salt) ; 220350-68-5 (HCl salt)
Shipping Condition	Ambient Temperature

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Chemical Name: ((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)

Synonym: Hepsera ; Preveon ; bis(POM)-PMEA

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=[P](OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)COCCN1C(N=CN=C2N)=C2N=C1

A simple and specific stability- indicating RP-HPLC method for routine assay of adefovir dipivoxil in bulk and tablet dosage form
By Darsazan, Bahar; Shafaati, Alireza; Mortazavi, Seyed Alireza; Zarghi, Afshin
From Iranian Journal of Pharmaceutical Research (2017), 16(1), 132-139

Development and validation of RP-HPLC method for the determination of adefovir dipivoxil in bulk and in pharmaceutical formulation
By Ahmed, Zaheer; Gopinath, B.; Shetty, A. Sathish Kumar; Sridhar, B. K.
From E-Journal of Chemistry (2009), 6(2), 469-474

Adefovir Dipivoxil is chemically ((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate). It is also known as Hepsera ; Preveon ; bis(POM)-PMEA. Adefovir Dipivoxil is supplied with detailed characterization data compliant with regulatory guideline. Adefovir Dipivoxil can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Adefovir.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Adefovir Dipivoxil

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SZ CAT No:	: SZ-A075001
CAS No	: 142340-99-6
Mol.F.	: C20H32N5O8P
Mol.Wt.	: 501.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 220350-60-7 (HBr salt) ; 220350-52-7 (Sulfate salt) ; 220350-68-5 (HCl salt)

SZ CAT No:	: SZ-A075004
CAS No	: 220350-68-5
Mol.F.	: C20H32N5O8P : HCl
Mol.Wt.	: 501.5 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 220350-60-7 (HBr salt) ; 220350-52-7 (Sulfate salt) ; 142340-99-6 (free base)

SZ CAT No:	: SZ-A075003
CAS No	: 220350-52-7
Mol.F.	: C20H32N5O8P : 1/2(H2SO4)
Mol.Wt.	: 501.5 : 1/2(98.1)
Inv. Status	: Custom Synthesis
Rel. CAS No	: 220350-60-7 (HBr salt) ; 142340-99-6 (free base) ; 220350-68-5 (HCl salt)

Adefovir Dipivoxil