Abacavir-1-O-pyrimidine Derivative

SZ CAT No:	SZ-A049045
CAS No	NA
Mol.F.	C16H17Cl2N9O3
Mol.Wt.	454.3
Inv. Status	Custom Synthesis

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Chemical Name: N-(2-Amino-4-(((1R,4S)-4-(((2-amino-6-chloro-5-formamidopyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)amino)-6-chloropyrimidin-5-yl)formamide

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=CNC1=C(Cl)N=C(N)N=C1OC[C@@H]2C=C[C@H](NC3=NC(N)=NC(Cl)=C3NC=O)C2

Stability indicating RP-HPLC method development and validation for determination of abacavir sulphate in tablet dosage form
By Ithape, Aniket B.; Deshpande, Padmanabh B.; Shelke, Priyanka
From International Journal of Pharmacy and Pharmaceutical Research (2020), 17(4), 670-680

A new stability indicating method was developed and validated for the simultaneous estimation of Lamivudine and Abacavir in tablet dosage form by RP-HPLC
By Rajamahanti, Santoshi G.; Annapurna, N.; Santosh, T.; Durga, B.; Raziya, S. K.
From Research Journal of Pharmaceutical, Biological and Chemical Sciences (2017), 8(3), 407-421

A validated stability-indicating RP-HPLC method for abacavir sulfate in the presence of degradation products, its process-related impurities and identification of oxidative degradant by LC-MS/MS
By Ragham, Pramod Kumar; Chandrasekhar, Kothapalli B.; Reddy, J. Rudraprasad; Kasturi, Krishna Mohan
From Indo American Journal of Pharmaceutical Research (2015), 5(1), 463-473

Abacavir-1-O-pyrimidine Derivative is chemically N-(2-Amino-4-(((1R,4S)-4-(((2-amino-6-chloro-5-formamidopyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)amino)-6-chloropyrimidin-5-yl)formamide. Abacavir-1-O-pyrimidine Derivative is supplied with detailed characterization data compliant with regulatory guideline. Abacavir-1-O-pyrimidine Derivative can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Abacavir.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Abacavir-1-O-pyrimidine Derivative

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