Vigabatrin EP Impurity B (HCl)

Synthesis and characterization of potential impurities of Vigabatrin-An anti epileptic drug
Kishore Karumanchi, Senthil Kumar Natarajan, Sunil Gadde, Ramadas Chavakula, Raghu Babu Korupolu & Kishore Babu Bonige
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 49, 2019 - Issue 3 Pages 359-366

Influence of the mobile phase composition on hyphenated ultraviolet and charged aerosol detection for the impurity profiling of vigabatrin
University of Würzburg, Institute for Pharmacy and Food Chemistry, 97074, Würzburg, Germany
Journal of Pharmaceutical and Biomedical Analysis
Volume 201, 15 July 2021, 114110

Vigabatrin EP Impurity B (HCl) is chemically (2E)-2-(2-Aminoethyl)but-2-enoic acid Hydrochloride (as per EP) ; (E)-2-(2-Aminoethyl)but-2-enoic acid hydrochloride (as per USP). It is also known as Vigabatrin USP Related Compound B. Vigabatrin EP Impurity B (HCl) is supplied with detailed characterization data compliant with regulatory guideline. Vigabatrin EP Impurity B (HCl) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vigabatrin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.