Trimetazidine EP Impurity I

Stability indicating HPTLC determination of Trimetazidine as bulk drug and in pharmaceutical formulations
Simmy O Thoppil, Rita MCardoza, P.D Amin
Journal of Pharmaceutical and Biomedical Analysis Volume 25, Issue 1, April 2001, Pages 15-20
 
Design of Experiments–Design Space Approach for Development of Chaotropic Chromatography Method for Determination of Trimetazidine Dihydrochloride and Two Impurities
Nenad Milošević, Ana Vemić, Jelena Čolović, Nađa Kostić & Anđelija Malenović
Chromatographia volume 80, pages585–592(2017)
 
Computer—Assisted Optimization and Validation of LC Analysis of Trimetazidine Dihydrochloride and Its Impurities
Mirjana B. Medenica, Darko P. Ivanovic, Igor B. Popovic, Andjelija M. Malenovic, Biljana S. Jancic
Journal of Chromatographic Science, Volume 46, Issue 5, May-June, Pages 430–435
 
Factor Optimization Study to Develop and Validate a Reversed-Phase Thin-Layer Chromatography Method for the Determination of Trimetazidine Dihydrochloride and Its Reported Impurities in Pharmaceuticals
Suzan Mahmoud Soliman
JPC - Journal of Planar Chromatography - Modern TLC Volume/Issue: Volume 32: Issue 4 Page Count: 273–283

Trimetazidine EP Impurity I is chemically 1-Methyl-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride (as per EP). It is also known as N-methyltrimetazidine (EP). Trimetazidine EP Impurity I is supplied with detailed characterization data compliant with regulatory guideline. Trimetazidine EP Impurity I can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trimetazidine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.