Triamcinolone Acetonide EP Impurity B

Resolution and quantitation of triamcinolone acetonide and its coformulated drug in the presence of its impurities and degradation products by HPTLC and HPLC
By Abbas, Samah S.; Hegazy, Maha A.; Hendawy, Hassan A. M.; Weshahy, Soheir A.; Abdelwahab, May H.
From Journal of AOAC International (2018), 101(4), 981-991
 
Stability indicating HPTLC determination of triamcinalone acetonide in bulk drug and sterile injectable suspension
By Kulyadi, Girish Pai; Sathyanarayana, Muddukrishna Badamane
From Journal of Young Pharmacists (2016), 8(4), 430-435

Development and validation of a stability-​indicating HPLC-​UV method for the determination of triamcinolone acetonide and its degradation products in an ointment formulation
By van Heugten, A. J. P.; de Boer, W.; de Vries, W. S.; Markesteijn, C. M. A.; Vromans, H.
From Journal of Pharmaceutical and Biomedical Analysis (2018), 149, 265-270
 

Triamcinolone Acetonide EP Impurity B is chemically 9-Fluoro-11β,21-dihydroxy-16α,17-(1-methylethylidenedioxy)pregna-1,4,14-triene-3,20-dione (as per EP) ; (9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-(11β,16α)-pregna-1,4,14-triene-3,20-dione) (as per USP). It is also known as Triamcinolone Acetonide USP Related Compound B ; Δ14-Triamcinolone Acetonide. Triamcinolone Acetonide EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Triamcinolone Acetonide EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Triamcinolone Acetonide.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.