Salbutamol EP Impurity B

Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography
AmandineDispasaVincentDesfontainebBertylAndriaPierreLebrunacDorinaKotonidAdrianClarkedDavyGuillarmebPhilippeHuberta
Journal of Pharmaceutical and Biomedical Analysis
Volume 134, 5 February 2017, Pages 170-180
 
Evolved gas analysis during thermal degradation of salbutamol sulphate
Fabio Sonvico, Victoria Coleman, Daniela Traini & Paul M. Young
Journal of Thermal Analysis and Calorimetry volume 120, pages789–794 (2015)
 
A chromatography-free synthesis of racemic salbutamol hemisulfate
AgatheVanoostLaurentPetit
Tetrahedron Letters
Volume 61, Issue 28, 9 July 2020, 152126

Salbutamol EP Impurity B is chemically (1RS)-2-[(1,1-Dimethylethyl)amino]-1-(4-hydroxyphenyl)ethanol (as per EP) . It is also known as Salbutamol BP Impurity C ; Albuterol USP Related Compound I ; Levalbuterol USP Related Compound B ; Buctopamine ; t-Butylnorsynephrine. Salbutamol EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Salbutamol EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Salbutamol .

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.