Paracetamol Dimer

Thermodynamic properties of paracetamol impurities 4-nitrophenol and 4′-chloroacetanilide and the impact of such impurities on the crystallisation of paracetamol from solution
René R.E.Steendam, LeilaKeshavarz, Briande Souza, Patrick J.Frawley
The Journal of Chemical Thermodynamics Volume 133, June 2019, Pages 85-92
 
Impact of Paracetamol Impurities on Face Properties: Investigating the Surface of Single Crystals Using TOF-SIMS
Sara Ottoboni, Michael Chrubasik, Layla Mir Bruce, Thai Thu Hien Nguyen, Murray Robertson, Blair Johnston,Iain D. H. Oswald, Alastair Florence, and Chris Price
Cryst. Growth Des. 2018, 18, 5, 2750–2758
 
Separation and determination of impurities in paracetamol, codeine and pitophenone in the presence of fenpiverinium in combined suppository dosage form
Jiří Vojta, Pavel Hanzlík, Aleš Jedlička, Pavel Coufal
J Pharm Biomed Anal. 2015 Jan;102:85-92.
 
Effects of a structurally related substance on the crystallization of paracetamol
Ali Saleemi, I. I. Onyemelukwe & Zoltan Nagy
Frontiers of Chemical Science and Engineering volume 7, pages79–87(2013)

Paracetamol Dimer is chemically N,N'-(6,6'-dihydroxy-[1,1'-biphenyl]-3,3'-diyl)diacetamide. Paracetamol Dimer is supplied with detailed characterization data compliant with regulatory guideline. Paracetamol Dimer can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paracetamol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.