Olmesartan Medoxomil EP Impurity C

Development and Validation of a Stability-Indicating Liquid Chromatographic Method for Estimating Olmesartan Medoxomil Using Quality by Design
Sarwar Beg, Gajanand Sharma, O.P. Katare, Shikha Lohan, Bhupinder Singh
Journal of Chromatographic Science, Volume 53, Issue 7, August 2015, Pages 1048–1059
 
Stability Indicating RP-HPLC Method Development and Validation for Simultaneous Quantification of 15 Organic Impurities of Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide in Combined Dosage Form
Pritesh R. Desai, Priti J. Mehta & Avani B. Chokshi
Chromatographia volume 82, pages819–833(2019)

Olmesartan Medoxomil EP Impurity C is chemically (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-methylethenyl)-2-propyl-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazole-5-carboxylate (as per EP). It is also known as Dehydro Olmesartan Medoxomil ; Anhydro Olmesartan Medoxomil ; Olmesartan Medoxomil Olefinic Impurity (USP) ; Olmesartan Medoxomil Methylvinyl Impurity. Olmesartan Medoxomil EP Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Olmesartan Medoxomil EP Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Olmesartan.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.