Loteprednol Impurity 2

Potential Use of Cyclodextrin Complexes for Enhanced Stability, Anti-​inflammatory Efficacy, and Ocular Bioavailability of Loteprednol Etabonate
By Soliman, Osama Abd El-Aazeem; Mohamed, Elham Abdel Monem; El-Dahan, Marwa Salah; Khatera, Nabil Abdullah Ali
From AAPS PharmSciTech (2017), 18(4), 1228-1241
 
Determination of edetate disodium dihydrate in loteprednol and tobramycin ophthalmic suspension by RP-​HPLC
By Xue, Qi; Yang, Longhua
From Zhongguo Yaoye (2012), 21(1), 24-25

An HPLC method to evaluate purity of a steroidal drug, loteprednol etabonate
By Yasueda, Shin-ichi; Higashiyama, Masayo; Shirasaki, Yoshihisa; Inada, Katsuhiro; Ohtori, Akira
From Journal of Pharmaceutical and Biomedical Analysis (2004), 36(2), 309-316

Loteprednol Impurity 2 is chemically 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl ethyl carbonate. Loteprednol Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Loteprednol Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Loteprednol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.