Fosphenytoin Impurity E

Glucuronidation of Prodrug Reactive Site: Isolation and Characterization of Oxymethylglucuronide Metabolite of Fosphenytoin
Thomas M Annesley, Stephen Kurzyniec, Gerald D Nordblom, Nathan Buchanan, William Pool, Michael Reily, Rasmy Talaat, William L Roberts
Clinical Chemistry, Volume 47, Issue 5, 1 May 2001, Pages 910–918

A new method for simultaneous quantification of fosphenytoin, phenytoin and its primary metabolite 5-(4-hydroxyphenyl)-5-phenylhydantoin in whole blood by ultra-performance liquid chromatography-tandem mass spectrometry
Takayoshi Suzukia,⁎ , Tadashi Ogawaa , Jun Ueyamab , Masae Iwaia , Fumio Kondoa , Hiroshi Seno
Legal Medicine Volume 34, September 2018, Pages 64-69

Fosphenytoin Impurity E is chemically Phosphoric acid dibenzyl ester 2,5-dioxo-4,4-diphenyl-imidazolidin-1-ylmethyl ester;. Fosphenytoin Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Fosphenytoin Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosphenytoin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.