Fluocinolone Acetonide EP Impurity B 

Stability-​indicating chromatographic determination of hydroquinone in combination with tretinoin and fluocinolone acetonide in pharmaceutical formulations with a photodegradation kinetic study
By Abbas, Samah S.; Elghobashy, Mohamed R.; Bebawy, Lories I.; Shokry, Rafeek F.
From RSC Advances (2015), 5(54), 43178-43194
 
Determination of fluocinolone acetonide by liquid chromatography
By Ohta, Miyako
From Iyakuhin Kenkyu (1981), 12(2), 456-61
 
Quantitative determination of fluocinolone acetonide and -​acetonide acetate in formulated products by high-​pressure liquid chromatography
By Bailey, F.; Brittain, P. N.
From Journal of Pharmacy and Pharmacology (1972), 24(6), 425-8
 

Fluocinolone Acetonide EP Impurity B  is chemically (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-3-oxoandrosta-1,4-diene-17-carboxylic Acid. It is also known as Fluocinolone Acetonide-20-Carboxylic Acid . Fluocinolone Acetonide EP Impurity B  is supplied with detailed characterization data compliant with regulatory guideline. Fluocinolone Acetonide EP Impurity B  can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fluocinolone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.