Efavirenz Cyclobutenylindole Impurity

Development and validation of a HPLC analytical assay method for efavirenz tablets: a medicine for HIV infections
Osnir de Sá Viana1 , Flávia Patrícia Morais Medeiros2 , Severino Grangeiro-Júnior2 , Miracy Muniz Albuquerque1 , Mônica Felts La Roca Soares1-3, José Lamartine Soares-Sobrinho1-3, Lariza Darlene Santos Alves1 , Larissa Araújo Rolim1 , Keyla Emanuelle Ramos da Silva1 , Pedro José Rolim-Neto
Braz. J. Pharm. Sci. vol.47 no.1 São Paulo Jan./Mar. 2011
 
Investigation of the solvent-dependent photolysis of a nonnucleoside reverse-transcriptase inhibitor, antiviral agent efavirenz
Maryam A Jordaan and Michael Shapi
Antiviral Chemistry and Chemotherapy 2017: 1–11
 
Method Development and Validation for Related Impurities of Efavirenz by RP-HPLC Method
Desaraju Bhargavi, Bhukya Babu Rao, Gangarapu Kiran, Thumma Gouthami & Vasudha Bakshi
TACL 7 (5) 2017 pp 737 – 747
 

Efavirenz Cyclobutenylindole Impurity is chemically Ethyl 5-chloro-2-cyclobutenyl-3-(trifluoromethyl)-1H-indole-1-carboxylate (as per USP). Efavirenz Cyclobutenylindole Impurity is supplied with detailed characterization data compliant with regulatory guideline. Efavirenz Cyclobutenylindole Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Efavirenz.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.