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Donepezil Impurity 18

SZ目录编号 SZ-D003047
CAS 号 110406-97-8
分子式 C11H15ClO2
分子量 214.7
投资状态 Custom Synthesis


Disclaimer

SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

化学名称: 4-(3-Chloropropyl)-1,2-dimethoxybenzene

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

微笑: COC(C=C(CCCCl)C=C1)=C1OC

Donepezil Impurity 18 is chemically 4-(3-Chloropropyl)-1,2-dimethoxybenzene. Donepezil Impurity 18 is supplied with detailed characterization data compliant with regulatory guideline. Donepezil Impurity 18 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Donepezil.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

New gradient high-performance liquid chromatography method for determination of donepezil hydrochloride assay and impurities content in oral pharmaceutical formulation
Stella Kafkala ∗, Stella Matthaiou, Pandora Alexaki, Morfis Abatzis, Antonios Bartzeliotis, Maria Katsiabani
Journal of Chromatography A, 1189 (2008) 392–397
 
Identification and characterization of potential impurities of donepezil
K.V.S.R. Krishna Reddy a, J. Moses Babu a, P. Anil Kumar b, E.R.R. Chandrashekar b, Vijayavitthal T. Mathad b, S. Eswaraiah b, M. Satyanarayana Reddy b, K. Vyas
Journal of Pharmaceutical and Biomedical Analysis 35 (2004) 1047–1058
 
An Improved and Efficient Process for the Production of Donepezil Hydrochloride: Substitution of Sodium Hydroxide for n-Butyl Lithium via Phase Transfer Catalysis
Navanath Niphade, Anil Mali, Kunal Jagtap, Ramesh Chandra Ojha, Pravinchandra J. Vankawala, and Vijayavitthal T. Mathad
Organic Process Research & Development 2008, 12, 731–735
 
Analytical Method Development and Validation for the Analysis of Donepezil Hydrochloride and Its Related Substances Using Ultra Perfomance Liquid Chromatography
Mahalingam V* , Kalaivani R A, Somanathan T, Vijayabaskar S
International Journal of Pharmaceutical and Clinical Research 2017; 9(5): 417-424

  • We need to receive valid purchase order with Bill to & Ship to address.
  • The quotation ID needs to be mentioned in the purchase order.
  • You will receive order confirmation prior to dispatch which need to be verified for any error in product, pack size, prices.

Delivery time:
  • In Stock product will dispatch in 24 h after receipt of purchase order. It usually take 2-3 days to receive products in India and 5-6 working days for export customer depending on destination.
  • The custom synthesis products would be dispatched as per quoted timeline.

Shipping:
  • There will be 100 USD towards logistic charges per shipment if we used our FedEx. There will not be any charge if we use your FedEx/DHL Account. Depending on part shipment logistic charges will be added.
  • For countries dispatch by courier is not allowed where product would be dispatched in cargo mode as per agreed Inco term.

Additional Charges:
  • Controlled substance charges need to follow as per quotation. The specific inputs are required for controlled substance because regulatory status will differ based on destination.
  • Cold Shipment Charges needs to be considered as per quotation.
  • For ice pack there are no additional charges.

Technical Queries:
  • All technical queries need to raise within 15 days of product receipt. Thereafter it will be our resolved at our discretion.

Reach to Us:
  • All communication will be addressed to standards@synzeal.com
  • SynZeal emphasize on formal communication which is required for smooth processing of the purchase order. It helps multiple people to remain informed about all details.
  • For specific purpose, there are below e-mail address to be used.
  • It is recommended to include standards@synzeal.com always in CC while communicating to other e-mail address.
  • SynZeal is committed for promptly responding all communication however if sometime urgent comes us you can use our WhatsApp customer care channel (+91 70690 37751) to reach to customer support team. You can also request call back on WhatsApp and our customer support team will reach to you in defined timeframe.