Domperidone EP Impurity A

Stability indicating simultaneous determination of domperidone (DP), methylparaben (MP) and propylparaben by high performance liquid chromatography (HPLC)
Mohammed Shahid Ali ∗, Mohsin Ghori, Aamer Roshanali Khatri
Journal of Pharmaceutical and Biomedical Analysis 41 (2006) 358–365
 
The Ultra-Performance Liquid Chromatography Determination of Domperidone and Its Process-Related Impurities
Laura Curtin Whelan, Michael Geary, Mary Wharton, Paul Sweetman
Journal of Chromatographic Science, Volume 53, Issue 2, February 2015, Pages 226–232
 
A Single Gradient Stability-Indicating Reversed-Phase LC Method for the Estimation of Impurities in Omeprazole and Domperidone Capsules
Raja Kumar Seshadri,*,1 Thummala Veera Raghavaraju,1 and Ivon Elisha Chakravarthy
Sci Pharm. 2013 Apr-Jun; 81(2): 437–458.

Domperidone EP Impurity A is chemically Des[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone ; 4-(6-Chloro-1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)piperidine ; 5-Chloro-1-piperidin-4-yl-1,3-dihydrobenzimidazol-2-one ; 5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone. Domperidone EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Domperidone EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Domperidone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.