Diosmin Impurity 1

Identification and Determination of Related Substances in Diosmin Bulk Drug and Pharmaceutical Formulations by HPLC and HPLC–MS
Imene Adouani  Mingluo Du  Tai-Jun Hang
Chromatographia (2013) 76:499–508
 
Oxidation of hesperidin into diosmin using ionic liquids
V. Thanh Nguyen , T. Kim-Chi Huynh , Thanh-Danh Nguyen and T. Kim-Dung Hoang
Org. Commun. 12:2 (2019) 101-108
 
A New, Simple Colorimetric Method For Assaying Diosmin, And Flavonoids In Daflon Tablets And Orange Peel Extracts
S. A. Mir*, A. A. Ahangar, A. S. Bhat
International Journal of PharmTech Research Vol.5, No.2, pp 341-348.

Diosmin Impurity 1 is chemically 3-hydroxy-4-methoxybenzoic acid. Diosmin Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Diosmin Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diosmin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.