Colchicine

Liquid chromatography-​tandem mass spectrometry for the determination of colchicine in postmortem body fluids. Case report of two fatalities and review of the literature
By Cheze Marjorie; Deveaux Marc; Pepin Gilbert
From Journal of analytical toxicology (2006), 30(8), 593-8.
 
Fast determination of colchicine by TLC-​densitometry from pharmaceuticals and vegetal extracts
By Bodoki E; Oprean R; Vlase L; Tamas M; Sandulescu R
From Journal of pharmaceutical and biomedical analysis (2005), 37(5), 971-7
 

Colchicine is chemically N-[(7S,12aM)-1,2,3,10-Tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (as per EP); (S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-acetamide (as per USP). Colchicine is supplied with detailed characterization data compliant with regulatory guideline. Colchicine can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Colchicine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.