Clozapine Nitroso EP Impurity C (TFA Salt)

Validated LC–MS-MS Method for the Determination of Quetiapine in Human Plasma: Application to a Pharmacokinetic Study
Ryh-Nan Pan, Benjamin Pei-Chung Kuo, Li-Heng Pao
Journal of Chromatographic Science, Volume 50, Issue 3, March 2012, Pages 277–282
 
Characterization of forced degradation products of clozapine by LC-DAD/ESI-Q-TOF.
Skibiński , Trawiński , Komsta , Bajda
Journal of Pharmaceutical and Biomedical Analysis, 04 Sep 2016, 131:272-280

Clozapine Nitroso EP Impurity C (TFA Salt) is chemically 8-chloro-11-(4-nitrosopiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine 2,2,2-trifluoroacetate. Clozapine Nitroso EP Impurity C (TFA Salt) is supplied with detailed characterization data compliant with regulatory guideline. Clozapine Nitroso EP Impurity C (TFA Salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Clozapine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.