Chlorphenamine EP Impurity D

Gas-liquid chromatographic determination of chlorpheniramine in blood plasma
Edward Townley, Isidoro Perez, and Peter Kabasakalian
Anal. Chem. 1970, 42, 14, 1759–1761
 
Validation of a HPLC quantification of acetaminophen, phenylephrine and chlorpheniramine in pharmaceutical formulations: capsules and sachets
A. Marı´n, E. Garcı´a, A. Garcı´a, C. Barbas
Journal of Pharmaceutical and Biomedical Analysis 29 (2002) 701–714
 
Development and Validation of a HPLC Method for Chlorphenamine Maleate Related Substances in Multicomponents Syrups and Tablets
Larisa Alagić-Džambić*, Midhat Vehabović, Edina Čekić, Mirsad Džambić
International Journal of Pharmacy Teaching & Practices 2014, Vol.5, Issue 3, 997-1001

Chlorphenamine EP Impurity D is chemically (2RS)-2-(4-chlorophenyl)-4-(dimethylamino)-2-(pyridin-2-yl)butanenitrile hydrochloride (as per EP). Chlorphenamine EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Chlorphenamine EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Chlorphenamine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.