Betaxolol EP Impurity B

LC and LC–MS/MS studies for the identification and characterization of degradation products of acebutolol
UdayRakibe, RaviTiwari, AnandMahajan, VipulRane, PravinWakte
Journal of Pharmaceutical Analysis Volume 8, Issue 6, December 2018, Pages 357-365
 
Enantioselective Bioanalysis of Beta-Blocking Agents: Focus on Atenolol, Betaxolol, Carvedilol, Metoprolol, Pindolol, Propranolol and Sotalo
Gabriele Egginger and Wolfgang Lindner, Christel Vandenbosch and Desire Luc Massart
Biomedical chromatography, vol. 7, 277-295 (1993)
 
Chirality recognition for assessing the enantiomeric purity of Betaxolol
Vinod Kumar Vashistha, Ravi Bhushan
Tetrahedron: Asymmetry 26 (2015) 304–311

Betaxolol EP Impurity B is chemically (2RS)-1-[4-(2-Hydroxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol (as per EP). It is also known as Betaxolol hydroxyethyl analog (USP). Betaxolol EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Betaxolol EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Betaxolol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.