Adefovir Dipivoxil Hydrochloride

A simple and specific stability- indicating RP-​HPLC method for routine assay of adefovir dipivoxil in bulk and tablet dosage form
By Darsazan, Bahar; Shafaati, Alireza; Mortazavi, Seyed Alireza; Zarghi, Afshin
From Iranian Journal of Pharmaceutical Research (2017), 16(1), 132-139

Development and validation of RP-​HPLC method for the determination of adefovir dipivoxil in bulk and in pharmaceutical formulation
By Ahmed, Zaheer; Gopinath, B.; Shetty, A. Sathish Kumar; Sridhar, B. K.
From E-Journal of Chemistry (2009), 6(2), 469-474

Adefovir Dipivoxil Hydrochloride is chemically ((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate) Hydrochloride. It is also known as Hepsera ; Preveon ; bis(POM)-PMEA. Adefovir Dipivoxil Hydrochloride is supplied with detailed characterization data compliant with regulatory guideline. Adefovir Dipivoxil Hydrochloride can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Adefovir.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.