Tadalafil Impurity 3

N° de SZ CAT:	SZ-T007017
Número CAS	2520114-84-3
Mol.F.	C21H19N3O4
Peso Molecular	377.4
Status de Fatura	Custom Synthesis

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Nome Químico: (6S,12aS)-6-(3,4-Dihydroxyphenyl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: O=C([C@]1([H])CC2=C([C@H](C3=CC=C(O)C(O)=C3)N14)NC5=C2C=CC=C5)N(C)CC4=O

Quantification of Genotoxic Impurities in Tadalafil by Simple and Sensitive Gas Chromatography Technique
Ajit Anerao,Bhushan Patil,Vishal Solse &Chandrakant Patil
Analytical Chemistry Letters Volume 9, 2019 - Issue 4 Pages 518-525

Chiral Separation of Two Pairs of Enantiomers of Tadalafil by High-Performance Liquid Chromatography
Wenhui Gao, Zhefeng Zhang, Zhiwei Li, and Guijian Liang
Journal of Chromatographic Science, Vol. 45, September 2007

Fast ultra‐high‐performance liquid chromatography with diode array and mass spectrometry method for determination of tadalafil drug substance and its impurities
Ludovit Schreiber Radoslav Halko Milan Hutta
Biomedical Chromatography Volume31, Issue12 December 2017 e4020

Validation and stability indicating RP-HPLC method for the determination of tadalafil API in pharmaceutical formulations
B. Prasanna Reddy , K. Amarnadh Reddy and M. S. Reddy
Research In Pharmaceutical Biotechnology Vol. 2(1), pp. 001-006

Stability-indicating methods for determination of tadalafil in presence of its degradation product
Moataz A.Yehia*, Mamdouh R.Rezk, Mohamed A.El-Sayed, Mohamed Abdel Kawy
ACAIJ, 14(9) 2014 [351-362]

Tadalafil Impurity 3 is chemically (6S,12aS)-6-(3,4-Dihydroxyphenyl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione . Tadalafil Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Tadalafil Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tadalafil.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Tadalafil Impurity 3

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N° de SZ CAT:	: SZ-T007001
Número CAS	: 171596-29-5
Mol.F.	: C22H19N3O4
Peso Molecular	: 389.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007002
Número CAS	: 171596-27-3
Mol.F.	: C22H19N3O4
Peso Molecular	: 389.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007003
Número CAS	: 629652-72-8
Mol.F.	: C22H19N3O4
Peso Molecular	: 389.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007004
Número CAS	: NA
Mol.F.	: C22H19N3O4 : HCl : 3(H2O)
Peso Molecular	: 389.4 : 36.5 : 3(18.0)
Status de Fatura	: Limited Stock

N° de SZ CAT:	: SZ-T007005
Número CAS	: NA
Mol.F.	: C22H19N3O6
Peso Molecular	: 421.4
Status de Fatura	: Under Synthesis

N° de SZ CAT:	: SZ-T007006
Número CAS	: 1978322-99-4
Mol.F.	: C22H19N3O6
Peso Molecular	: 421.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007007
Número CAS	: 2747958-44-5
Mol.F.	: C22H19N3O6
Peso Molecular	: 421.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007008
Número CAS	: 2520114-46-7
Mol.F.	: C22H17N3O5
Peso Molecular	: 403.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007009
Número CAS	: 1978322-98-3
Mol.F.	: C22H19N3O6
Peso Molecular	: 421.4
Status de Fatura	: Out of Stock, Custom Synthesis

N° de SZ CAT:	: SZ-T007010
Número CAS	: 2378614-29-8
Mol.F.	: C22H19N3O5
Peso Molecular	: 405.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007011
Número CAS	: 1093940-69-2
Mol.F.	: C21H18N4O4
Peso Molecular	: 390.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007012
Número CAS	: 14907-27-8
Mol.F.	: C12H14N2O2 : HCl
Peso Molecular	: 218.3 : 36.5
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007013
Número CAS	: 171752-68-4
Mol.F.	: C20H18N2O4 : HCl
Peso Molecular	: 350.4 : 36.5
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007014
Número CAS	: 171489-59-1
Mol.F.	: C22H19ClN2O5
Peso Molecular	: 426.9
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007015
Número CAS	: NA
Mol.F.	: C22H19N3O4
Peso Molecular	: 389.4
Status de Fatura	: Limited Stock

N° de SZ CAT:	: SZ-T007016
Número CAS	: 171596-43-3
Mol.F.	: C20H18N2O4
Peso Molecular	: 350.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007D01
Número CAS	: 960226-55-5
Mol.F.	: C22H16D3N3O4
Peso Molecular	: 392.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007017
Número CAS	: 2520114-84-3
Mol.F.	: C21H19N3O4
Peso Molecular	: 377.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007018
Número CAS	: NA
Mol.F.	: C21H19N3O4
Peso Molecular	: 377.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007019
Número CAS	: 1797099-86-5
Mol.F.	: C21H19N3O4
Peso Molecular	: 377.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007020
Número CAS	: 20850-43-5
Mol.F.	: C8H7ClO2
Peso Molecular	: 170.6
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007021
Número CAS	: 749864-17-3
Mol.F.	: C20H18N2O4
Peso Molecular	: 350.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007022
Número CAS	: 2520114-95-6
Mol.F.	: C24H20ClN3O5
Peso Molecular	: 465.9
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007023
Número CAS	: 7797-83-3
Mol.F.	: C8H6O3
Peso Molecular	: 150.1
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007024
Número CAS	: 495-76-1
Mol.F.	: C8H8O3
Peso Molecular	: 152.1
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007025
Número CAS	: 769-30-2
Mol.F.	: C8H8O3
Peso Molecular	: 152.1
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007026
Número CAS	: 326-61-4
Mol.F.	: C10H10O4
Peso Molecular	: 194.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-T007027
Número CAS	: NA
Mol.F.	: C22H18N4O5
Peso Molecular	: 418.4
Status de Fatura	: Inquire

N° de SZ CAT:	: SZ-T007028
Número CAS	: NA
Mol.F.	: C24H20Cl2N2O6
Peso Molecular	: 503.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-T007029
Número CAS	: NA
Mol.F.	: C22H21N3O5
Peso Molecular	: 407.4
Status de Fatura	: Custom Synthesis