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Tacrolimus EP Impurity G

N° de SZ CAT:SZ-T005008
Número CAS144490-63-1
Mol.F.C44H69NO12
Peso Molecular804.0
Status de FaturaCustom Synthesis

Nome Químico: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19S,26aS)-5,19-Dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a- octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone (as per EP); (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19S,26aS)-8-Allyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a,hexadecahydro-5,19-dihydroxy-3-{(E)-2-[1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14,16,dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone (as per USP)

Sinônimo: Tacrolimus 19-epimer (USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: CO[C@@H]1[C@]2([H])[C@@H](OC)C[C@@H](C)[C@](O)(O2)C(C(N3CCCC[C@@]3([H])C(O[C@H](/C(C)=C/[C@@H]4CC[C@@H](O)[C@H](OC)C4)[C@H](C)[C@@H](O)CC([C@H](CC=C)/C=C(C)/C[C@H](C)C1)=O)=O)=O)=O

Tacrolimus EP Impurity G is chemically (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19S,26aS)-5,19-Dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a- octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone (as per EP); (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19S,26aS)-8-Allyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a,hexadecahydro-5,19-dihydroxy-3-{(E)-2-[1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14,16,dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone (as per USP). It is also known as Tacrolimus 19-epimer (USP). Tacrolimus EP Impurity G is supplied with detailed characterization data compliant with regulatory guideline. Tacrolimus EP Impurity G can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tacrolimus.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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