Rivaroxaban Impurity 63

N° de SZ CAT:	SZ-R017100
Número CAS	53935-71-0
Mol.F.	C5H3ClO2S
Peso Molecular	162.6
Status de Fatura	Custom Synthesis

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Nome Químico: 2-Chlorothiophene-3-carboxylic acid

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: OC(C(C=CS1)=C1Cl)=O

Development and validation of stability indicating UPLC method for the determination of Rivaroxaban in bulk and finished products and identification of degradation products by LCMS
By Ali, Syed Mastan; Ramachandran, D.
From Journal of Applicable Chemistry (Lumami, India) (2021), 10(3), 291-301

Validated LC-MS/MS method for the determination of three genotoxic impurities in rivaroxaban drug substance
By Korlakunta, Vijaya Gouri; Dasari, Vijaya Bharathi; Sharma, Hemant Kumar; Nowduri, Annapurna; Bonige, Kishore Babu; Chavakula, Ramadas
From European Journal of Biomedical and Pharmaceutical Sciences (2020), 7(8), 492-500

Development of a stability-indicating HPLC method and a dissolution test for rivaroxaban dosage forms
By Souri, Effat; Mottaghi, Siavash; Zargarpoor, Mohammad; Ahmadkhaniha, Reza; Jalalizadeh, Hassan
From Acta Chromatographica (2016), 28(3), 347-361

Rivaroxaban Impurity 63 is chemically 2-Chlorothiophene-3-carboxylic acid. Rivaroxaban Impurity 63 is supplied with detailed characterization data compliant with regulatory guideline. Rivaroxaban Impurity 63 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rivaroxaban.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Rivaroxaban

N° de SZ CAT:	: SZ-R017001
Número CAS	: 366789-02-8
Mol.F.	: C19H18ClN3O5S
Peso Molecular	: 435.9
Status de Fatura	: In Stock

Rivaroxaban EP Impurity B

N° de SZ CAT:	: SZ-R017002
Número CAS	: 1429334-00-8
Mol.F.	: C16H19N3O5
Peso Molecular	: 333.3
Status de Fatura	: In Stock

Rivaroxaban Aminomethyl Base Impurity

N° de SZ CAT:	: SZ-R017003
Número CAS	: 446292-10-0
Mol.F.	: C14H17N3O4
Peso Molecular	: 291.3
Status de Fatura	: In Stock
Rel. CAS No	: 898543-06-1 (HCl salt) ; 1251952-81-4 (HBr salt) ; 1251952-66-5 (Sulfate salt)

Rivaroxaban Aminomethyl HCl Impurity

N° de SZ CAT:	: SZ-R017004
Número CAS	: 898543-06-1
Mol.F.	: C14H17N3O4 : HCl
Peso Molecular	: 291.3 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 446292-10-0 (free base) ; 1251952-81-4 (HBr salt) ; 1251952-66-5 (Sulfate salt)

Rivaroxaban CMTCA Impurity

N° de SZ CAT:	: SZ-R017005
Número CAS	: 97799-98-9
Mol.F.	: C6H6CINOS
Peso Molecular	: 175.6
Status de Fatura	: In Stock

Rivaroxaban EP Impurity F

N° de SZ CAT:	: SZ-R017006
Número CAS	: 24065-33-6
Mol.F.	: C5H3ClO2S
Peso Molecular	: 162.6
Status de Fatura	: In Stock
Rel. CAS No	: 112158-46-0 (Na salt)

Rivaroxaban Descarbonyl Impurity

N° de SZ CAT:	: SZ-R017007
Número CAS	: 721401-53-2
Mol.F.	: C18H20CIN3O4S
Peso Molecular	: 409.9
Status de Fatura	: In Stock

Rivaroxaban EP Impurity E

N° de SZ CAT:	: SZ-R017008
Número CAS	: 1415566-28-7
Mol.F.	: C19H19N3O5S
Peso Molecular	: 401.4
Status de Fatura	: In Stock

Rivaroxaban Diol

N° de SZ CAT:	: SZ-R017009
Número CAS	: 1160170-00-2
Mol.F.	: C19H20ClN3O6S
Peso Molecular	: 453.9
Status de Fatura	: Out of Stock, Custom Synthesis

Rivaroxaban N-Methylphthalimide Impurity

N° de SZ CAT:	: SZ-R017010
Número CAS	: 550-44-7
Mol.F.	: C9H7NO2
Peso Molecular	: 161.2
Status de Fatura	: In Stock

Rivaroxaban Open-Ring Acid Impurity (HCl salt)

N° de SZ CAT:	: SZ-R017011
Número CAS	: 931117-61-2
Mol.F.	: C19H20ClN3O6S : HCl
Peso Molecular	: 453.9 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 931204-39-6 (free base)

Rivaroxaban EP Impurity J

N° de SZ CAT:	: SZ-R017012
Número CAS	: 1632463-24-1
Mol.F.	: C38H36CI2N6O10S2
Peso Molecular	: 871.8
Status de Fatura	: In Stock

Rivaroxaban Open-Ring N-Methyl Impurity

N° de SZ CAT:	: SZ-R017013
Número CAS	: 1807455-76-0
Mol.F.	: C25H24Cl2N4O6S2
Peso Molecular	: 611.5
Status de Fatura	: In Stock

Rivaroxaban Phthalamide Dimer

N° de SZ CAT:	: SZ-R017014
Número CAS	: 1365267-36-2
Mol.F.	: C36H36N6O10
Peso Molecular	: 712.7
Status de Fatura	: In Stock

Rivaroxaban Phthalimido Descarbonyl Impurity (R-Isomer)

N° de SZ CAT:	: SZ-R017015
Número CAS	: 446292-07-5
Mol.F.	: C21H21N3O5
Peso Molecular	: 395.4
Status de Fatura	: In Stock

Rivaroxaban EP Impurity G

N° de SZ CAT:	: SZ-R017016
Número CAS	: 446292-08-6
Mol.F.	: C22H19N3O6
Peso Molecular	: 421.4
Status de Fatura	: In Stock

Rivaroxaban EP Impurity A

N° de SZ CAT:	: SZ-R017017
Número CAS	: 865479-71-6
Mol.F.	: C19H18CIN3O5S
Peso Molecular	: 435.9
Status de Fatura	: In Stock

Rivaroxaban EP Impurity D

N° de SZ CAT:	: SZ-R017018
Número CAS	: 1365267-35-1
Mol.F.	: C29H32N6O9
Peso Molecular	: 608.6
Status de Fatura	: In Stock

Rivaroxaban 3-Hydroxy Metabolite

N° de SZ CAT:	: SZ-R017019
Número CAS	: 1160169-97-0
Mol.F.	: C19H18ClN3O6S
Peso Molecular	: 451.9
Status de Fatura	: Custom Synthesis

Rivaroxaban 4-Hydroxy Metabolite

N° de SZ CAT:	: SZ-R017020
Número CAS	: 1161719-51-2
Mol.F.	: C19H18ClN3O6S
Peso Molecular	: 451.9
Status de Fatura	: Custom Synthesis

Rivaroxaban Methyl Ester Impurity

N° de SZ CAT:	: SZ-R017021
Número CAS	: NA
Mol.F.	: C16H19N3O6
Peso Molecular	: 349.3
Status de Fatura	: In Stock

Rivaroxaban Degradate -1

N° de SZ CAT:	: SZ-R017022
Número CAS	: NA
Mol.F.	: C13H19N3O2 : HCl
Peso Molecular	: 249.3 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 1816946-19-6 (free base)

Rivaroxaban Oxo Amine Amide Impurity

N° de SZ CAT:	: SZ-R017023
Número CAS	: 1838139-24-4
Mol.F.	: C19H18ClN3O5S
Peso Molecular	: 435.9
Status de Fatura	: In Stock

Aminophenylmorpholinone

N° de SZ CAT:	: SZ-R017024
Número CAS	: 438056-69-0
Mol.F.	: C10H12N2O2
Peso Molecular	: 192.2
Status de Fatura	: In Stock
Rel. CAS No	: 1640884-60-1 (HCl salt)

Rivaroxaban Impurity E

N° de SZ CAT:	: SZ-R017025
Número CAS	: 1252018-10-2
Mol.F.	: C13H17ClN2O3
Peso Molecular	: 284.7
Status de Fatura	: In Stock

Rivaroxaban Impurity 1

N° de SZ CAT:	: SZ-R017026
Número CAS	: 530-62-1
Mol.F.	: C7H6N4O
Peso Molecular	: 162.2
Status de Fatura	: In Stock

Rivaroxaban Impurity 2

N° de SZ CAT:	: SZ-R017027
Número CAS	: 85-41-6
Mol.F.	: C8H5NO2
Peso Molecular	: 147.2
Status de Fatura	: In Stock
Rel. CAS No	: 33081-78-6 (Na salt) ; 1074-82-4 (K salt)

Rivaroxaban Impurity 3

N° de SZ CAT:	: SZ-R017028
Número CAS	: 1074-82-4
Mol.F.	: C8H4NO2 : K
Peso Molecular	: 146.1 : 39.1
Status de Fatura	: In Stock
Rel. CAS No	: 85-41-6 (free base) ; 33081-78-6 (Na salt)

Rivaroxaban Impurity 4

N° de SZ CAT:	: SZ-R017029
Número CAS	: 1445-69-8
Mol.F.	: C8H6N2O2
Peso Molecular	: 162.2
Status de Fatura	: In Stock
Rel. CAS No	: 20116-60-3 (Na salt) ; 477282-81-8 (K salt)